Comparison of LFP-physiomarkers for DBS programming
Objective: To evaluate clinical usability of LFP(local field potentials)-physiomarkers and lead localisation for selection of suitable DBS electrode configurations. Background: Selection of optimal contacts in…Adult-onset stereotypy — An atypical presentation of frontotemporal dementia
Objective: Describe a case of adult-onset stereotypy with abulia. Background: Stereotypy is a non-goal directed but distractible behavior repeated continuously. While common in the pediatric…Study of eye movements as a tool in the diagnosis hereditary ataxias
Objective: To study ocular movements (ocular pursuit, nystagmus and saccades) in the most frequent ataxias (SCA2, SCA3 and Friedreich's ataxia), to find out which variables…Oscillaotory activity in the globus pallidus internus in patients with Parkinson’s disease
Objective: To quantify the characteristics of oscillatory neurons in the GPi in patients with PD. Background: Abnormal oscillatory activity has been predicted to play a…Pallidal surgery and physiological mechanism in choreic movements
Objective: To investigate the effect of deep brain stimulation (DBS) or coagulation of the internal globus pallidus (GPi) for choreic movements of various disorders and…Neuromuscular electrical stimulation for the treatment of jaw-closing dystonia
Objective: To measure whether neuromuscular electrical stimulation (NMES) increases jaw-opening distance and improves quality-of-life in jaw-closing dystonia patients. Background: An index case with progressive supranuclear…Correlations between genetics and cortical dysfunction of paroxysmal kinesgenic dyskinesia
Objective: To delineate the cortical function of paroxysmal kinesigenic dyskinesia (PKD) and correlate with the genotypes of patients. Background: PKD is characterized by episodic involuntary movements…Characterization of the motor phenotype and striatal muscle analysis in a mouse model of hereditary spasticity
Objective: Characterize the motor phenotype and contractile force characteristics of skeletal plantar flexor muscles in a mutant mouse model for spasticity. This model displays a…Impact of cathine and carthinone use among Parkinson’s disease Patients
Objective: Evaluate cathine and cathinone’s effect on alertness, energy, sleep pattern, and tremor among Parkinson’s disease patient. Background: Khat, a plant that contains amphetamine like…Asymmetrical striatal dopamine transporter binding correlates with excess contralateral rest tremor
Objective: To investigate the relationship between striatal dopamine transporter binding and rest tremor. Background: In vivo dopamine transporter imaging is a useful tool for distinguishing…
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