The changes in alpha-synuclein level and oscillatory activity of substantia nigra by nigral electrical stimulation
Objective: We aimed to clarify the relationships between the alpha-synuclein level and abnormal oscillatory activity and their changes induced by deep brain stimulation of the…Low Beta-Band Suppression as a Tool for DBS Contact Selection for Akinetic-rigid Symptoms in Parkinson’s Disease
Objective: To assess the utility of beta-band suppression as a tool for contact selection in patients undergoing nucleus subthalamicus (STN) deep brain stimulation (DBS) for…Adaptive Deep Brain Stimulation for Parkinson’s Disease: from tolerability to patient preference and clinical outcomes
Objective: To characterize patient preference and clinical outcomes in subjects receiving adaptive Deep Brain Stimulation (aDBS) for Parkinson’s Disease (PD). Background: Local field potential (LFP)…Detection of Levodopa induced Dyskinesia based on spectral features from subthalamic-LFP and sensorimotor-ECoG
Objective: To detect the presence of Levodopa induced Dyskinesia (LID) in Parkinson’s disease (PD) patients based on spectral characteristics from invasive cortico-subthalamic recordings using machine…Tourette Syndrome with Functional Overlay: A Diagnosis Challenge and The Role of Electrophysiological Study
Objective: To highlight the role of electrophysiological study (Ephy) as a useful diagnostic tool. Background: Tics with functional overlay are characterised by acute worsening of…Motor control of finger individuation and strength in patients with Parkinson’s disease and Spinocerebellar Ataxia type 12
Objective: Compare finger individuation (FI) and maximum finger strength in healthy control, patients with Parkinson’s Disease (PD) and Spinocerebellar ataxia type12 (SCA12). We also examined…Encoding of action plans and confidence in the human basal ganglia-thalamic circuit
Objective: The basal ganglia (BG) are known to play a vital role in action initiation and inhibition, studied with several simple behaviors in multiple species.…Detecting clinical fluctuations in chronic biomarker recordings: experiences with chronic subthalamic peak beta band recordings in a large Parkinson’s disease patient cohort
Objective: Since the understanding of electrophysiological biomarker dynamics during every-day activities is crucial for adaptive deep brain stimulation (aDBS), this study aims to investigate characteristics…Neurophysiological analysis of the posterior subthalamic area in a patient with Holmes’ tremor
Objective: To analyze the neuronal firing patterns in the posterior subthalamic area (PSA) in a Holmes’ tremor (HT) patient who underwent DBS implantation procedure. Background:…Polyneuropathy in Parkinson’s disease: cross-sectional analysis of the Bochum Parkinson Nerve Study cohort
Objective: To describe the prevalence of large-fiber polyneuropathy (PNP) in people with PD and examine differences between subjects with or without PNP. Background: Non-motor symptoms…
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