The feasibility of detailed phenotyping of muscle mitochondrial respiratory chain function and content in Parkinson’s disease
Objective: We aimed to determine: 1) the feasibility of obtaining and characterising skeletal muscle; and 2) if muscle mitochondrial respiratory chain (MRC) function and content…Magnetic Property Characterization of Deep Gray Matters in Patients with Alzheimer’s diseases, Dementia with Lewy Bodies and Parkinson’s Disease Dementia using Quantitative Susceptibility Mapping
Objective: The purpose of this study was to characterize magnetic properties of deep gray matters in Alzheimer's diseases (AD), dementia with Lewy bodies (DLB) and…Dual hit model of Parkinson’s disease propagation using MRI biomarkers and partial least squares path modeling
Objective: This study aimed using multimodal MRI to test two models of Parkinson’s disease propagation and investigated how the models were influenced by the presence…Predicting Longitudinal Atrophy in Parkinson’s Disease using SIR model
Objective: To predict longitudinal brain changes in Parkinson's disease (PD) using an agent-based model. Background: Considerable evidence suggests that α-synuclein(α-syn) behaves in a prion-like fashion,…Differences in subthalamic oscillatory neuronal activity associated with severity in Parkinson’s disease
Objective: To investigate whether altered neuronal activity in the subthalamic nucleus (STN) is associated with severity in patients with Parkinson’s disease (PD). Background: PD is…Sex-related disease differences in Parkinson’s disease
Objective: To highlight differences in clinical disease parameters between sexes in a cohort of Parkinson’s disease (PD) patients. Background: PD is a progressive neurodegenerative disorder…Effects of Co-Morbidities on Sleep Patterns in Parkinson’s Disease: A Study of 84 Ibadan Patients
Objective: To assess the effects of co-morbidities on sleep patterns in PD. Background: Parkinson’s disease is a progressive neurodegenerative disease. The non-motor symptoms are said…Vascular factors in Parkinson’s disease with cognitive impairment
Objective: To review the relationship between vascular related factors and cognitive impairment in Parkinson's disease. Background: Parkinson's disease is a chronic, progressive, neurodegenerative disease that…Alpha synuclein BAC transgenic mice as a preclinical model for disease-modifying therapies in Parkinson’s disease
Objective: The aim of this study is to make preclinical mice models for disease-modifying therapies in Parkinson's disease. Background: The prodromal stage of Parkinson's disease…Severity of Motor Symptoms in Parkinson’s Disease in Kazakhstan (on the example of the city of Almaty)
Objective: Determine the severity of motor symptoms with Parkinson's disease using the MDS-UPDRS scale. Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by…
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