The longevity gene Klotho and its CSF protein profiles as modifier for Parkinson´s disease in a longitudinal study
Objective: Our objective was to evaluate phenotype modifying effects of variants in longevity genes in PD. Background: Parkinson´s disease (PD) has a large phenotypic variability,…Neuropsychological and behavioral profile of patients with isolated REM sleep behaviour disorders (iRBD) and patients with RBD associated with Parkinson’s Disease (PDRBD)
Objective: We aimed to compare the neuropsychological and psychobehavioral profile of patients with iRBD and PDRBD. Background: REM Sleep Behavior Disorder (RBD) is considered as…The impact of clinical care coordination on patient quality of life in the Atypical Parkinsonism clinic
Objective: To assess the impact of clinical care coordination on patient quality of life in the Atypical Parkinsonism clinic. Background: The Atypical Parkinsonian Syndromes of…Caregiver burden does not improve in the long-term after deep brain stimulation for Parkinson disease
Objective: To evaluate if subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson disease (PD) impacts caregiver burden (CB) and to determine which patient factors…Relationship between parkinsonism and upper extremity function in patients with Parkinson’s disease
Objective: To examine the relationship between upper extremity function and the Movement Disorders Society-Unified Parkinson’s Disease Rating Scale part III (MDS-UPDRS-III) for use as a…Genetics of Parkinson’s in India – Young Onset Parkinson’s Disease (GOPI-YOPD) – A Preliminary Demographic profile
Objective: To see the demographic pattern of Parkinson's Disease (PD) patients of India with onset of clinical symptoms prior to 50 years of age or…Population Exposure-Response Modeling of the Effects of Apomorphine Sublingual Film on QTc in Patients With Parkinson’s Disease and “OFF” Episodes
Objective: To characterize the relationship between plasma apomorphine concentrations and QTc (QT interval corrected for heart rate) in patients with Parkinson’s disease (PD) and “OFF”…Improving outcomes in hospitalized Parkinson’s patients
Objective: Evaluate an inpatient intervention to reduce rates of hospital related complications in hospitalized patients with Parkinson’s disease (PD). Background: Several interventions have been suggested…Frequency of impulse control disorder in Parkinson’s disease: insights from the Luxembourg cohort
Objective: To establish the frequency of impulse control disorder (ICD) in idiopathic Parkinson’s disease (IPD) and analyze contributing factors. Background: To establish the frequency of…Contribution of pedunculopontine nucleus cholinergic neurons to L-DOPA-induced dyskinesia and PD motor deficits in hemi-parkinsonian rats
Objective: To determine if chemogenetic and pharmacological modulation of pedunculopontine nucleus (PPN) cholinergic neurons can alter L-DOPA-induced dyskinesia and gait deficits in hemi-parkinsonian rats. Background:…
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