Abnormal pattern of brain glucose metabolism in multiple system atrophy
Objective: To define and cross-validate the brain glucose metabolic abnormalities in patients with a clinical diagnosis of Multiple System Atrophy (MSA). Background: Despite the availability…Improving Hospital Outcomes through the Aware in Care Ambassador Program
Objective: The objective is to analyze the impact of the Aware in Care (AIC) Ambassador program in accomplishing its three goals regarding hospitalization of people…The interplay between asymmetric dopaminergic degeneration, brain structural changes and cognition in de-novo PD: The PPMI dataset
Objective: To characterize the impact of asymmetric dopaminergic degeneration, measured with I123-ioflupane SPECT (DATSCAN), on cortical integrity and cognitive deficits, in de-novo right-handed PD patients.…The feasibility of cognitive telerehabilitation in patients with Parkinson´s disease: The pilot data
Objective: The aim of this study was to focus on the feasibility and potential benefits of cognitive telerehabilitation (CTR) in patients with Parkinson´s disease (PD).…Cortical pathology in Glucocerebrosidase mutation carriers with anxiety: An MRI study
Objective: To employ Magnetic Resonance Imaging (MRI) and investigate structural pathology in the cortex of Glucocerebrosidase (GBA) gene mutation carriers. Background: Mutations in the GBA…Characterizing the genetic architecture of Parkinson’s disease in Latinos
Objective: By performing the first genome-wide association study (GWAS) of Parkinson’s disease (PD) in Latinos, we seek to interrogate the genetic architecture of PD in…Characterizing Global Cohorts with Monogenic Parkinson’s Disease
Objective: To clinically and genetically characterize a global sample of subjects with monogenic Parkinson’s disease (mPD) and unaffected mutation carriers. Background: Publications on patients with…Compartment-specific blockade of dopamine uptake in nigrostriatal pathway reveals role for nigral dopamine function in movement frequency in open-field
Objective: Inhibition of tyrosine hydroxylase activity in the substantia nigra (SN) produces a significant reduction in locomotor motor activity commensurate with decreased dopamine (DA) content…Nucleus basalis of Meynert free-water distinguishes and predicts cognitive impairment and longitudinally correlates with cognitive changes in early Parkinson’s disease
Objective: To explore diffusion-based MRI assessments of the nucleus basalis of Meynert (nbM) as a neuroimaging biomarker of cognitive abilities and longitudinal cognitive changes in…Intrinsic Remodeling of the Fovea is Correlated with Contrast Sensitivity Loss in Parkinson’s Disease
Objective: The aim of the study was to determine a technical parameter of foveal pathology that is best suited for discriminating Parkinson’s disease (PD) eyes…
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