Understanding characteristics, healthcare resource use and costs of patients with Parkinson’s disease prior to and after diagnosis of cognitive impairment
Objective: The primary goal of this retrospective cohort study was to understand characteristics, healthcare resource use (HCRU) and costs of patients with PD before and…Associations between subjective and objective cognitive decline in Parkinson’s disease
Objective: To evaluate associations between objective and subjective cognitive function over time in Parkinson’s disease (PD) using data from a clinical trial that enrolled patients…Multimodal EEG-MRI based machine learning model in identifying Parkinson’s disease with mild cognitive impairment
Objective: To evaluate the diagnostic value of quantitative electroencephalogram (qEEG) and structure Magnetic resonance (sMR) in identifying mild cognitive impairment in Parkinson’s disease (PD-MCI) via…Significant hypometabolism in the posterior parietal cortex and precuneus in Parkinson’s disease with GBA mutations: [18F]FDG PET study
Objective: We explored [18F]FDG PET findings of PD patients with GBA mutation. Background: Parkinson’s disease (PD) with glucocerebrosidase (GBA) mutations is characterized by early onset…The ROPAD (Rostock International Parkinson’s Disease Study) study: Towards defining the genetic epidemiology of the disease
Objective: ROPAD is an international, multicenter, epidemiological study that aims at a better understanding of the contribution of genetics to Parkinson’s disease (PD) based on…A novel peptide reduces α-synuclein levels and neurodegeneration in cell, invertebrate, and mammalian models of Parkinson’s disease
Objective: To identify and test the effectiveness of a novel peptide to reduce α-synuclein levels and neurodegeneration in cell and animal models of Parkinson’s disease…Inter-network connectivity dynamics underlie compensatory mechanisms in prodromal Parkinson’s disease
Objective: We aimed to investigate the dynamics of inter-network connectivity among non-manifesting GBA and LRRK2 mutation carriers. Background: The prodromal phase of Parkinson’s disease (PD)…Retinal thinning and disease worsening in Lewy body diseases
Objective: To assess longitudinal changes of retinal thickness measurements and their role as biomarkers of disease progression in patients with Lewy body diseases (LBDs). Background:…Brain cholinergic dysfunction in patients with isolated REM sleep behavior disorder: A clinical and 11C-Donepezil PET follow-up study
Objective: In this follow-up study, we aimed to explore the temporal changes in brain acetylcholinesterase activity and cognitive function of iRBD patients. Background: Isolated REM…Time Series Analysis Applied to EEG Shows Increased Global Connectivity During Motor Activation in PD Patients Compared to Controls
Objective: To apply time series analysis techniques to EEG studies to study connectivity changes during motor activation in a cohort of Parkinson´s disease subjects (PD)…
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