PRECISE-PD: From pathophysiology to precision medicine for Parkinson’s disease
Objective: To propose a mechanism-based progression model of Parkinson’s disease (PD) by combining genetic, imaging, and longitudinal clinical data from a large cohort of patients.…Parkinson’s disease Polygenic Risk Factor Scores in Patients with Inflammatory Bowel Disease
Objective: To assess the genetic risk factors for Parkinson’s disease (PD) in a large population of patients with inflammatory bowel disease (IBD), as compared to…Identification of genetic alterations and SNCA mutation in Parkinson’s disease patients of Coimbatore Population, India
Objective: The aim of the study is to analyze the genetic alterations in SNCA gene and dopamine transporter in 22 PD patients of Coimbatore population.…Longitudinal analysis of the modified Hoehn and Yahr disease stage in PD-1101, a Phase 1b clinical study of VY-AADC01
Objective: To describe changes over the first year in disease severity and activities of daily living using modified Hoehn and Yahr (mH&Y) stage and UPDRS…Parkinson’s Disease Treatments and Outcomes: US v Non-US Patients
Objective: To determine if there are differences in treatment patterns and outcomes in US patients, who often must pay for some of their care, and…Longitudinal digital observation of the holistic quality of the life of patients with Parkinson’s disease
Objective: The aim of this study is the development of a digital concept for a longitudinal assessment of quality of life during the various stages…The Effectiveness of Rehabilitation Using Honda Walking Assist in Parkinson’s Disease Patients; The Gait Analysis by a Markerless Motion Capture System
Objective: We verified the usefulness of an automatic gait and posture analyzer for estimation of rehabilitation using Honda Walking Assist (HWA). Background: The abnormal posture…Diagnostic journeys of people with Parkinson’s disease in Kenya, sub-Saharan Africa
Objective: To explore the experiences of people living with Parkinson’s disease (PWPD) with regards to their diagnostic journeys among public and private hospital settings in…Modeling of Parkinson’s disease by damaging dopaminergic neurons
Objective: Analysis of the simulation of Parkinson's disease in rats using 6-OHDA.Analysis of the simulation of Parkinson's disease in rats using 6-OHDA. Background: The mechanism…Spectrum of parkinsonian phenotypes associated with GCH1 mutation.
Objective: To describe the heterogeneity of parkinsonism in patients with GCH1 mutations. Background: Dopa-responsive dystonia (DRD) is an inherited disorder that responds dramatically to levodopa…
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