Identification and analysis of differential miRNA in exosomes of dopaminergic neurons overexpressing α-synuclein
Objective: The aim of this study was to compare the miRNA expression in secreted exosomes from dopaminergic neurons overexpressing α-synuclein with healthy neurons. Background: Exosomes,…Quantitative analysis of DaT uptake and neuromelanin MR contrast in patients with Parkinson’s disease and healthy controls
Objective: To examined quantitative measures of neuromelanin (NM) MRI and DaT-SPECT imaging of the SN and striatum to distinguish PD patients from healthy control subjects…Paraneoplastic and neuronal surface antibodies in Parkinson’s disease and atypical parkinsonian disorders
Objective: To investigate the prevalence of paraneoplastic and antineuronal antibodies in the serum and cerebrospinal fluid (CSF) from patients with Parkinson´s disease (PD) and atypical…Mineralization pattern of the deep gray matter by susceptibility-weighted magnetic resonance imaging to differentiate Parkinsonian disorders
Objective: To study mineralization pattern of the deep gray matter by susceptibility-weighted (SWI) magnetic resonance imaging to differentiate Parkinson’s disease and atypical parkinsonian disorders like…Neuroprotective effect of exogenous melatonin on apoptosis of neuroadernergic neurons in a rat model of Parkinson’s disease
Objective: To investigate melatonin therapeutic potential effects in Parkinson’s disease. Background: Sleep disorders constitute major nonmotor features of Parkinson’s disease (PD) that have a substantial…Altered amplitude of low-frequency fluctuations and functional connectivity in excessive daytime sleepiness in Parkinson disease
Objective: The present study aimed to explore the neural mechanism of Excessive daytime sleepiness (EDS) in Parkinson disease (PD). Background: EDS is common in PD,…Effect of medication on lexical tone production in Cantonese patients with Parkinson’s Disease
Objective: To examine how dysarthria resulting from Parkinson’s Disease (PD) affects lexical tone production in Cantonese-speaking patients and to evaluate the effects of medication Background:…Vowel characteristics associated with Parkinson’s disease in Cantonese
Objective: Dopaminergic treatment has been reported to help motor problem associated with Parkinson's disease (PD), but not speech motor. The current study examined vowel articulation…Risk estimation in the years preceding diagnosis of Parkinson’s disease in the PREDICT-PD cohort
Objective: To test and refine the use of probability-based algorithms to identify individuals at high-risk of developing Parkinson’s disease (PD). Background: Neurodegeneration preceding a formal…GBA haploinsufficiency accelerated alpha synuclein pathology with altered lipid metabolism in a premotor model of Parkinson’s disease
Objective: To make Parkinson’s disease (PD) mice model and investigate the mechanism how glucocerebrosidase (gba) heterozygous mutations contribute to asyn pathology and development of PD.…
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