Public Awareness on Parkinson’s disease in Urban Central Asia
Objective: To assess public knowledge on PD in the two largest Central Asian countries, Uzbekistan and Kazakhstan. Background: Public awareness of Parkinson’s disease (PD) is…Neuroprotective Effects of A Combination of Curcumin and Mucuna Prurience in Rotenone Induced Mice Model of Parkinson’s Disease
Objective: In the current study we have evaluated possible synergistic neuroprotective effect of two Poly-Phenols from Curcumin and Mucuna Prurience. The combine treatment of Curcumin…Long-Duration Response to Levodopa in advanced Parkinson’s Disease: Relevance for RCT on Disease-Modifying therapies
Objective: (1) To investigate the natural history of Parkinson’s disease (PD) in a cohort of newly diagnosed patients and (2) the response to acute levodopa…The combined effect of repetitive transcranial magnetic stimulation and treadmill training in people with Parkinson’s disease – A randomized controlled trial
Objective: To evaluate the combined effect of repetitive transcranial magnetic stimulation (rTMS) on treadmill training in people with Parkinson’s disease (PD). Background: Previous studies showed…VY-AADC01 gene therapy in Parkinson’s disease: Interim results of the on-going Phase 1b PD-1101 trial
Objective: Evaluate the safety of VY-AADC01, an AAV2 gene therapy vector with human aromatic L-amino acid decarboxylase (AADC) administered bilaterally to the putamen using intraoperative…CLOVER-DBS: A Prospective, Multi-center Clinical Study with Blinding to Evaluate a Closed Loop Programming Algorithm for Directional Leads Based on External Feedback
Objective: To assess the feasibility and efficacy of a novel closed-loop programming algorithm (CLPA) for directional lead deep brain stimulation (DBS) based on objective feedback…Activities of Daily Living and Quality of Life in Patients with Advanced Parkinson’s Disease Who Are Treated with or Planning to Use Device-Aided Treatments
Objective: To correlate activities of daily living (ADL) and quality of life (QoL) in advanced Parkinson’s disease (APD) patients with ongoing or planned device-aided treatment…Rationale and Design of an Open-Label, Randomized, 26-Week Study Comparing Levodopa-Carbidopa Intestinal Gel to Optimized Medical Treatment on Non-Motor Symptoms in Patients with Advanced Parkinson’s Disease – INSIGHTS Study
Objective: To examine levodopa-carbidopa intestinal gel, LCIG (also known as carbidopa-levodopa enteral suspension in the US), on non-motor symptoms (NMS) compared with individually-optimized, conventional PD…An Objective Tool to Guide Target Selection for DBS in PD (GPi vs STN) – integration into Thomas Jefferson’s multidisciplinary Movement Disorders Center
Objective: After the creation of simple tool to aid in selection of the proper target for Deep Brain Stimulation (DBS) in Parkinson’s Disease (PD), our…Simple Programming Method in STN-DBS using directional lead
Objective: Consider a stimulation programming method that can be performed easily and in a short time. Background: Background: Since the subthalamic nucleus (STN) is a…
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