Increased and symmetric expression of rigidity in early Parkinson’s disease with abnormal REM sleep without atonia
Objective: The purpose of this study was to compare the level and bilateral expression of upper arm rigidity between people with early stage Parkinson’s disease…Evaluation of spike sorting algorithms applied to artificial spikes and to spikes recorded from the Subthalamic Nucleus of PD patients
Objective: To evaluate the variability in spike sorting results using different clustering algorithms Background: Extracellular currents recorded from the Subthalamic Nucleus (STN) of PD patients,…Freezing of gait in Parkinson’s disease consists of unique pressure-based gait phase transitions
Objective: To develop a method to detect freezing of gait in real time Background: Freezing of gait (FOG) is a major debilitating symptom and cause…Clinical feasibility of a wearable, conformable, sensor patch to monitor motor symptoms in Parkinson’s disease
Objective: 2-part pilot study to evaluate feasibility of a wearable sensor, the prototype NIMBLE system sensor patch, to assess motor symptoms in Parkinson’s disease (PD) patients.…Evaluation of the short-term and long-term effects of an intensive multidisciplinary collective rehabilitation program over 5 weeks in Parkinson’s patients followed in Lyon
Objective: We studied the value of collective (8 patients per group) intensive multidisciplinary collective rehabilitation in the short and long term. Background: Numerous studies have proved…Neuropsychological profile of corticobasal degeneration, progressive supranuclear palsy and frontotemporal dementia patients
Objective: To study and compare the neuropsychological profile of patients with corticobasal degeneration (CBD), progressive supranuclear palsy (PSP), non-fluent progressive aphasia (NFPA) and frontotemporal behavioral…MANF protects dopamine neurons and locomotion defect from Neurotoxin/Human alpha-synuclein-induced progressive Parkinson’s disease models in C.elegans.
Objective: To study whether Mesencephalic astrocyte-derived neurotrophic factor (MANF) has beneficial effects in parkinson disease and its intracellular mechanisms. Background: The distinguishing feature of Parkinson’s…Prediction of cognitive progression in Parkinson’s disease using three cognitive screening measures
Objective: To assess the utility of commonly used cognitive screening tools in predicting the transition to mild cognitive impairment (MCI) and/or dementia (PDD) in Parkinson’s…Spiral Analysis is a Promising Biomarker in LRRK2 G2019S carriers
Objective: To assess whether harboring a LRRK2 G2019S mutation is associated with abnormalities in spiral drawing, including in mutation carriers with Parkinson Disease (PD) as…Expression of OX40 and OX40 serum level in patients with Parkinson’s disease
Objective: Study the expression of OX40 gene and its serum levels could be measured to predict and confirm diagnosis of Parkinson's disease and help develop new…
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