The role of phosphodiesterase 4 in sleep disturbances in Parkinson’s disease
Objective: We aimed to assess the association between phosphodiesterase 4 (PDE4) expression and sleep disturbances in vivo using combined multimodal magnetic resonance imaging (MRI) and…Information transfer between subthalamic area and forearm muscles during tonic muscle activity in Parkinson’s patients
Objective: We compare information transfer between forearm muscles and two subthalamic regions, namely the subthalamic nucleus (STN) and the zona incerta (ZI), during an isometric…Calcium Channel Blocking Drugs and Risk of LRRK2 Parkinson’s Disease
Objective: To test the association between Parkinson’s disease (PD) and calcium channel blocker CCB use in individuals carrying LRRK2 mutations. Background: LRRK2 mutation penetrance is…The Superior Colliculus is impaired in de novo Parkinson’s disease patients
Objective: To study the function of the Superior Colliculus (SC) in de novo Parkinson’s disease (PD) patients. Background: The SC function is impaired in parkinsonian…High-Resolution Manometry (HRM) in Parkinson’s Disease (PD)
Objective: To characterize esophageal symptoms in PD using high-resolution Manometry. Background: Dysphagia is common in PD; its etiology multifactorial and its management challenging. In a retrospective…Non-motor symptoms in Parkinsons’s disease patients treated with levodopa-carbidopa intestinal gel infusion- the follow up study
Objective: To follow up the effect of continuous levodopa-carbidopa intestinal gel infusion (LCIG) on motor and non-motor symptoms in advanced Parkinson’s disease (aPD). Background: Non-motor…Brain metabolic patterns in progressive supranuclear palsy phenotypes
Objective: To describe changes in cerebral glucose metabolism in patients with different described clinical phenotypes of PSP and to correlate them with the clinical manifestations of the disease. Background:…Long-term Parkinson’s disease progression in PIGD and TD subtypes in the PPMI cohort
Objective: Analyze the disease progression and time of therapy initiation for tremor dominant (TD) and postural instability gait disorder (PIGD) subtypes in the PPMI cohort.…Pre-synaptic dopaminergic deficit in a patient with familial FTD
Objective: Clinical description of a patient with familial FTD with a rapidly progressive parkinsonism. Background: FTD typically presents with behavioral and cognitive deficits, but extrapyramidal…Palliative Care in Parkinson Disease
Objective: The objective of this study was to derive a baseline understanding of palliative care among the Parkinson disease (PD) patient population at a single…
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