Articles tagged "Parkinsonism"

2017 International Congress
Managing severe dyskinesia in Parkinson’s Disease using 24-hour Levodopa/Carbidopa Intestinal Gel Infusion
B. Cruse, D. Tsui, J. Griffith, H. Morales-Briceno, F. Chang, A. Ha, S. Kim, N. Wolfe, V. Kwan, N. Mahant, V. Fung (Westmead, Australia)
Objective: We report the effective treatment of troublesome dyskinesias in Parkinson’s disease (PD), unresponsive to 16-hour daytime infusions, using 24-hour Levodopa/Carbidopa Intestinal Gel (LCIG). Background:…
2017 International Congress
Preliminary results of 18F-DTBZ PET study in the patients with vascular parkinsonism
W.-Y. Lin, Y.-H. Weng, K.-J. Lin, C.-S. Lu (Taoyuan, Taiwan)
Objective: Our studies was designed to assess the dopaminergic pathway in the patients with vascular parkinsonism (VP). Background: VP develops as a consequence of heterogeneous…
2017 International Congress
Cognitive data in the Parkinson’s Progression Markers Initiative: Comparison of normative data approaches
K. Wyman-Chick, M. Barrett, P. Martin, C. Manning, S. Sperling (Charlottesville, VA, USA)
Objective: It is important to understand underlying psychometric properties of the cognitive tests included in the Parkinson’s Progression Markers Initiative (PPMI) dataset to interpret the…
2017 International Congress
Predict Cognitive Decline with Clinical Markers in Parkinson’s Disease
G. Pagano, T. Yousaf,, C. Loane, S. Polychronis, H. Wilson, B. Giordano, F. Niccolini, M. Politis (London, United Kingdom)
Objective: We investigated which clinical-ready and cost-effective markers are predictive of cognitive impairment (CI) in Parkinson’s disease (PD) in a cohort of 294 patients with…
2017 International Congress
Association of the GBA T369M polymorphism with motor and cognitive symptoms in Parkinson’s disease
A. Julius, Y.-H. Lin, M. Smith, J. Leverenz, D. Weintraub, J. Trojanoswski, V. Van Deerlin, B. Ritz, R. Rausch, J. Quinn, K. Chung, S. Factor, L. Rosenthal, T. Dawson, M. Albert, A. Espay, F. Revilla, J. Devoto, J. Goldman, G. Stebbins, B. Bernard, Z. Zbigniew, O. Ross, D. Dickson, D. Yearout, S.-C. Hu, C. Johnson, B. Cholerton, T. Montine, K. Edwards, C. Zabetian (Seattle, WA, USA)
Objective: To determine whether the GBA polymorphism T369M is associated with earlier age of onset, lower cognitive performance, and more severe motor impairment in Parkinson's…
2017 International Congress
Genome-wide DNA methylation analysis reveals epigenetic perturbations in Parkinson disease.
J. Young, S. Sivasankaran, L. Wang, A. Ali, A. Mehta, D. Davis, K. Belle, D. Dykxhoorn, C. Petito, G. Beecham, E. Martin, D. Mash, W. Scott, J. Vance (Miami, FL, USA)
Objective: Several environmental exposures are known to affect the risk for PD. Because DNA methylation is affected by environmental variables, we investigated whether brain region-specific…
2017 International Congress
The role of habenula and amygdala dysfunction in Parkinson’s disease patients with punding
V. Markovic, F. Agosta, E. Canu, A. Inuggi, I. Petrovic, I. Stankovic, F. Imperiale, T. Stojkovic, V. Kostic, M. Filippi (Belgrade, Serbia)
Objective: To assess whether a functional dysregulation of the habenula and amygdala, as modulators of the reward brain circuit, contributes to Parkinson’s disease (PD)-punding. Background:…
2017 International Congress
Beyond shuffling: Gait phenotypes in Parkinson’s Disease
L. Solis-Cohen, C. Ashton, D. Simon, M. Fox, D. Tarsy, R. Alterman, V. Vanderhorst, L. Shih (Boston, MA, USA)
Objective: To describe commonly observed gait phenotypes in a cohort of advanced Parkinson's Disease (PD) patients. Background: Gait disorders in PD are varied and complex. Even…
2017 International Congress
Clinical Criteria for Subtyping Parkinson’s Disease: Differences in imaging and CSF biomarkers and longitudinal progression
S.-M. Fereshtehnejad, Y. Zeighami, A. Dagher, R. Postuma (Montreal, QC, Canada)
Objective: To introduce a new practical classification method to assign individuals with Parkinson’s disease (PD) into distinct subtypes using baseline dataset, then to compare neuroimaging,…
2017 International Congress
Effect of object size and obstacle avoidance on of Reach-to-Grasp Actions in Individuals with Parkinson’s disease
S. Khacharoen, J. Tretriluxana, P. Srivanitchapoom, A. Pisarnpong, T. Chandharohit (Nakhon Pathom, Thailand)
Objective: To investigate the effect of object size and obstacle on reach-to-grasp (RTG) actions in individuals Parkinson's disease (PD). Background: Previous studies reported impairments of…