Decision making under uncertainty in medicated and un-medicated Parkinson’s disesase
Objective: To evaluate decision making under risk in Parkinson’s disease patients, both medicated and un-medicated states probing constituent cognitive operations driving choice. Background: Prior literature…eEF1A2 promotes cell survival and protects against MPP+-induced apoptotic neuronal death through the PI3K/Akt/mTOR pathway
Objective: To assess the correlation of eEF1A2 and PI3K/Akt/mTOR expression and investigate the pro-survival role of eEF1A2 in NG108-15 rodent neuroglioma cells. Background: Eukaryotic protein…A member of the HSP40/DNAJ family is a novel gene for early-onset parkinsonism
Objective: We aim to implicate novel genes/mutations using whole-exome sequencing (WES) in selected pedigrees. Background: Mutations have been identified in only 30% of familial parkinsonism.…Electrophysiological markers for emotional and cognitive impairment in Parkinson’s disease
Objective: This study aims to identify markers for emotional and cognitive dysfunctions in Parkinson’s disease (PD) using non-invasive electroencephalography (EEG). This study investigates event related…What strategies do Parkinson’s disease patients use for getting out of bed in the early morning? Preliminary results from home video analysis of 22 patients.
Objective: To classify PD patients’ getting out of bed strategies using home video analysis. Background: Getting out of bed represents a major difficulty of early…Validation of the MDS Research Criteria for Prodromal Parkinson’s Disease: longitudinal assessment in a REM sleep behavior disorder (RBD) cohort
Objective: 1) To calculate diagnostic accuracy of the Movement Disorder Society (MDS) prodromal criteria to predict conversion to Parkinson’s disease (PD) or dementia with Lewy…End of Life Care in Parkinson’s Disease
Objective: We aim to identify the current practice at the Royal Devon & Exeter NHS trust of managing Patients with PD at the end of…Prognosis and end-of-life status after emergency admissions in patients with Parkinson disease: a Japanese single center retrospective study
Objective: To investigate the status after the emergency admissions and to determine the cause and location of death in patients with Parkinson disease (PD). Background:…Istradefylline improves not only motor symptoms but also sleep disturbance, daytime sleepiness, and QOL of Parkinson’s disease patients.
Objective: This study analyzed the clinical effectiveness of istradefylline in terms of sleep disturbance in Parkinson’s disease (PD) patients. Background: A selective adenosine A2A receptor…Programming of deep brain stimulators in Parkinson’s disease with early motor complications (EARLYSTIM-study)
Objective: Recently the EARLYSTIM study showed the superior effect of subthalamic stimulation to best medical treatment in Parkinson`s disease with early motor complications. Background: EARLYSTIM…
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