Genetic Identification of early-onset parkinsonism among Norwegian patients
Objective: To investigate the genetic etiology of early-onset (AAO > 45 Years) parkinsonism. Background: Parkinsonism is a neurological syndrome characterized by resting tremor, rigidity, bradykinesia…Premotor phase of PD in two GBA mutation carriers
Objective: To identify premotor phase of Parkinson's disease (PD) in obligate GBA heterozygous carriers. Background: GBA mutation carriers are in greater risk of developing PD.…The correlation between N30 SEP and motor function in Parkinson’s disease
Objective: To investigate frontal N30 in Parkinson's disease (PD), and to examine the correlation between amplitude of frontal N30 and the degree of motor deficits.…Quantifying daily living transitions in patients with Parkinson’s disease using a body-fixed sensor
Objective: To test whether measures of everyday sit-to-walk and walk-to-sit differ between patients with Parkinson's disease (PD) and healthy older adults (HOA) and between mild…Lessons learned from the Nilotinib trial: Cardio-vascular conditions in parkinsonism
Objective: A retrospective records review of 9 patients that failed screening for a clinical trial was performed to examine the co-morbid cardiac manifestations of PD…Non-motor symptoms profiles in UK white Caucasian and Asian as well as overseas Thai and East Indian patients with Parkinson’s disease
Objective: To compare motor and non-motor symptoms (NMS) in white Caucasian (WC) and Asian patients with Parkinson's disease (PwP) living in the UK as well…Characterization of striatal TH-immunoreactive cells in chronic and acute L-DOPA treatment in a mice model of Parkinson´s disease
Objective: To characterize Tyrosine Hydroxylase immunoreactive cells (TH-ir) in a mouse model of hemiparkinsonism and L-DOPA induced dyskinesia. Background: L-DOPA-induced dyskinesias (LID) are a severe…Relative hypoglycemia induces acute chorea followed by chronic parkinsonism in a diabetic patient on hemodialysis: A case with sequential clinico-radiological correlate
Objective: To present a sequential clinico-radiological study of a diabetic patient on hemodialysis who developed acute chorea followed by chronic parkinsonism. Background: Hyperglycemic chorea is…Anti-GAD antibody cerebellar ataxia mimicking multiple system atrophy
Objective: To describe a case of anti-glutamic acid decarboxylase antibody (GAD-Abs)-associated cerebellar ataxia (CA), which presented with gradual dysautonomia and parkinsonism fulfilling criteria for MSA,…The role of cathepsin L involved in the activation of microglia and Parkinson’s disease
Objective: To investigate the role of lysosomal protease cathepsin L in the activation of microglia and the injury of dopaminergic neurons, and further to interpret…
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