Reduced lifespan and climbing ability observed in the overexpressing human α-synuclein without heat shock protein CNB115 in Parkinson’s disease drosophila line
Objective: To investigate the neurotoxic role of overexpressing α-synuclein without Heat Shock Protein CNB115 (HSP115) in Parkinson's disease Drosophila line. Background: Parkinson's disease (PD) is…Clinical exome sequencing – diagnostic yield in a sample of German patients with Parkinson’s disease
Objective: To assess the diagnostic yield of clinical exome sequencing (CES) in individuals with Parkinson's disease (PD) seen in a specialized movement disorder clinic. Background:…Two-step induction of dopaminergic neurons – Differentiation of leukapharesis-derived mesenchymal stem cells
Objective: The aim of the present study is to establish a reproducible in-vitro protocol to induce the human MSCs derived from peripheral blood, after mobilization…IL-6 and motor symptoms in Parkinson’s disease
Objective: To assess the concentration of interleukin-6 (IL-6) in serum of patients with PD and its relation to motor symptoms. Background: Participation of inflammatory mechanisms…LC3 deacetylation by SIRT1 is involved in neuroprotective effects of resveratrol in an MPTP mouse model of Parkinson’s disease
Objective: Our previous study has demonstrated that resveratrol (RV) enhanced clearance of misfolded α-synuclein proteins in cellular models of PD, with the activation of SIRT1…Involvement of peripheral immune system in the pathogenesis of Parkinson’s disease
Objective: To investigate the role of peripheral immune system in the pathogenesis of Parkinson's disease carrying LRRK2 risk variants. Background: Leucine-rich repeat kinase 2 (LRRK2)…Oral apomorphine film (APL-130277) produces no buccal mucosal irritation: Results of a toxicological study
Objective: Determine the tolerance of and potential for cheek pouch buccal mucosa irritation following the administration of apomorphine film (APL-130277). Background: APL-130277 is a sublingual…Exosomes-injection to reproduce a mouse model of Parkinson’s disease: A preliminary report
Objective: To explore the pathogenicity of exosomes derived from Parkinson's disease (PD) patients' serum and healthy control's serum in vivo and verify the prion-like propagation…Tremor frequency by iPhone® applications: Correlation with EMG analysis
Objective: To compare tremor frequency obtained by EMG and accelerometry analysis with three iPhone® applications. Background: Frequency as a property of tremor is a vital…PET examination of the monoamine transporter with 11C-beta-CIT
Objective: To investigate the utility of 11C-β-CIT PET scan on Parkinson's disease diagnosis. Background: The monoamine reuptake sites transport dopamine, noradrenaline and serotonin from the…
- « Previous Page
- 1
- …
- 342
- 343
- 344
- 345
- 346
- …
- 405
- Next Page »