Mild cognitive impairment is linked with white matter degeneration in the cortico-subcortical tracts in patients with Parkinson’s disease
Objective: Evaluate the correlation between brain tractography changes in patients with Parkinson's disease (PD) with and without mild cognitive impairment (MCI). Background: Up to 40%…Profile of depressive symptoms in Parkinson’s disease patients and a population-based elderly cohort
Objective: To examine the prevalences and profiles of depressive symptoms in Parkinson's disease (PD) patients and population-based control groups by using the Beck depression inventory.…Ambulatory assessment of tremor
Objective: To develop ambulatory assessment of tremor in Parkinson's disease (PD) throughout the day, in relationship to treatment and fluctuations in bradykinesia. Background: PD is…Disability is an independent predictor of falls and recurrent falls in people with Parkinson’s disease without a history of falls: A one-year prospective study
Objective: To determine predictors of all falls and recurrent falls in people with Parkinson's disease (PD) who had not fallen in the past year; and…Parkinsonian symptoms in patients with cervical dystonia treated with bilateral pallidal deep brain stimulation: A controlled study
Objective: To 1) evaluate the presence of Parkinsonian symptoms in patients with cervical dystonia treated with bilateral deep brain stimulation (DBS) of the globus pallidus…Development of a nanoherbaceutical containing natural L-DOPA from mucuna pruriens for the prevention and treatment of Parkinson’s disease in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced animal model
Objective: To prepare and evaluate the nanoherbaceutical formulation containing natural L-DOPA from Mucuna pruriens against the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced Parkinson's disease (PD). Background: PD is…A computational model of iron transport between the blood circulation and the brain
Objective: To create a mechanistic computational model of iron transport between the circulation and brain, permitting in silico investigation of homeostatic regulation of iron at…Does distance walked after two minutes predict total 6 minute walk test distance in people with Parkinson’s disease?
Objective: To determine if the distance walked in the first two minutes of the 6 Minute Walk Test (6MWT) accurately predicts the total distance walked…Swallowing difficulties in patients with Parkinson’s disease and Parkinsonian syndromes
Objective: To analyze the frequency and severity of swallowing difficulties in patients with Parkinson's disease (PD) and Parkinsonian syndromes. Background: Swallowing difficulties are common in…Improvement of freezing of gait with intestinal levodopa infusion in advanced Parkinson’s disease patients
Objective: To determine whether levodopa-carbidopa intestinal gel (LCIG) infusion is able to improve freezing of gait (FOG) in advanced Parkinson's disease (PD) patients. Background: FOG…
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