Determining and Leveraging Local Ancestry to Assess Individual-Level Risk: from the Global Parkinson’s Genetics Program
Objective: We develop a scalable pipeline leveraging existing tools to determine local ancestry for all individuals in the Global Parkinson’s Genetics Program (GP2), aiming to…Levels of change in interleukin-6 levels according to clinical forms of Parkinson’s disease in patients with and without Covid-19
Objective: Comparison of serum IL-6 levels in clinical forms Parkinson's disease (PD) patients with and without Сovid-19. Background: Changes in the treatment after infection with…Satisfaction with telemedicine of patients with movement disorders on the Pacific coast of Colombia.
Objective: Determine the level of satisfaction with the telemedicine consultation of patients with movement disorders on the Pacific coast of Valle del Cauca, in Colombia,…Association of fecal short-chain fatty acids with clinical severity and gut microbiota in Essential tremor and its differences from Parkinson’s disease
Objective: To investigate the fecal levels of short-chain fatty acids (SCFAs) in essential tremor (ET) patients, assess their relationships with clinical symptoms and gut microbiota,…monogenic parkinsonism in latin america: systematic review and meta-analysis
Objective: This study aims to assess the frequency, distribution and the minimum prevalence of monogenic Parkinsonism in Latin America (LA) Background: The prevalence of monogenic…May CSF biomarkers have a role in degenerative parkinsonian syndromes workup?
Objective: To evaluate the role of cerebrospinal fluid (CSF) biomarkers in the differential diagnosis of degenerative parkinsonian syndromes. Background: The differential diagnosis of degenerative parkinsonian…Preoperative motor deficits and depressive symptoms predict quality of life in patients with Parkinson’s disease at different time points after surgery for subthalamic stimulation.
Objective: This retrospective study explored whether preoperative motor, cognitive, and affective parameters predict QoL and QoL components at 6 and 12 months after STN-DBS surgery.…Comparison of biospecimens for α-synuclein seed amplification assays in Parkinson’s disease: A Systematic Review and Network Meta-Analysis
Objective: We performed meta-analysis to determine the diagnostic and differential diagnostic value of α-syn SAAs for PD, and to investigate the optimal specimens. Background: Alpha-synuclein…Parkinson’s Disease and Chronic Inflammatory Demyelinating Polyneuropathy: Broadening the Clinical Spectrum of VCP Mutations?
Objective: Valosin-containing protein (VCP) mutation causes a multiorgan disease characterized by inclusion body myopathy, Paget disease and frontotemporal dementia, more rarely by Charcot-Marie-Tooth disease type…Bridging the Gap between Statistical significance and Clinical Relevance: A Systematic Review of Minimum clinically important difference (MCID) thresholds of scales reported in trials of Movement Disorders
Objective: To provide a comprehensive review of various patient-reported outcome (PROs) used in movement disorders (MD) research and their MCID values reported in literature. Background:…
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