Pharmacokinetic-pharmacodynamic effects of apomorphine sublingual film (APL-130277) for the rapid management of OFF episodes in patients with Parkinson’s disease
Objective: Determine the pharmacokinetic/pharmacodynamic effects of APL-130277 on OFF episodes in patients with Parkinson's disease (PD). Background: APL-130277 is a sublingual film being studied in…Increased cellular co-localization of tau fragment 1-368 and alpha-synuclein in two mouse model of Parkinson’s disease
Objective: To examine the distribution of a novel tau pathology and its interaction with alpha-synuclein in two mouse model of Parkinson's disease (PD). Background: Cleavage…MRI guided high-intensity focused ultrasond for the treatment of essential tremor and Parkinson’s disease: Clinical outcome and radiological findings of unilateral thalamotomy
Objective: To report our clinical experience in the treatment of essential (ET) and Parkinson's disease (PD) tremor with MRI guided High-Intensity Focused Ultrasound (MRgHIFU). Background:…Pronounced beta oscillations are a characteristic of the cortico-basal ganglia loop of subacute and chronic animal models of Parkinson´s disease
Objective: To compare the power spectral densities of local field potentials recorded from the cortico-basal ganglia loop of a subacute (reserpine) and a chronic (6-OHDA)…How do we make mistakes diagnosing movement disorders?
Objective: Analyze diagnostic errors in a Movement Disorder Section (MDS) in a public hospital in Buenos Aires, Argentina. Background: Abnormal movements are a common complaint…Altered resting-state functional interhemispheric connectivity in Parkinson’s disease
Objective: To examine direct interhemispheric functional connectivity (FCi) in Parkinson's disease (PD) during resting-state fMRI and to investigate the relations between observed connectivity changes and…Comparison of DAT scan, cardiac MIBG scintigraphy, and cerebrospinal fluid 5HIAA levels in Parkinsonian syndrome
Objective: To assess the associations of presynaptic dopamine transporter (DAT scan), cardiac 123I-meta-iodobenzylguanidine (MIBG) scintigraphy, and cerebrospinal fluid (CSF) levels of 5-hydroxyindole acetic acid (5HIAA)…Suppression of dyskinesia in Parkinson’s disease by electrical stimulation of dorsal subthalamic nucleus tissue
Objective: The objectives of this study were to investigate suppression of dyskinesia in Parkinson's disease (PD) patients who had previously undergone deep brain stimulation (DBS)…The patterns of olfactory function in Parksinson’s disease patients with mild cognitive impairment
Objective: To examine relationship between olfactory dysfunction and PD-MCI, and investigated the patterns of olfactory function in subtypes of PD-MCI patients using the Korean version…Rapid eye movement sleep behavior disorder symptoms correlate with domains of cognitive impairment in Parkinson’s disease
Objective: To investigate (1) the domains of cognitive impairment in patients with Parkinson's disease (PD) and rapid eye movement sleep behavior disorder (RBD). (2) To…
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