DBS targeting: Validation of 3T MR image guided targeting using post-mortem 17T MR microscopy
Objective: This work helps validate the utility of direct targeting using 3T T1 inverted sequences with atlas application during planning for DBS electrode placement. We…Role of contact polarity on therapeutic impedances at two deep brain stimulation (DBS) targets
Objective: To demonstrate the role of contact polarity on therapeutic impedances at two DBS targets. Background: Neuromodulation with DBS is an established therapy for medically…A prospective study of patients’ expectations in subthalamic nucleus deep brain stimulation for Parkinson’s disease
Objective: To prospectively assess the long-term outcome of subthalamic nucleus (STN) deep brain stimulation (DBS) and the relationship with patients' expectations and satisfaction. Background: Subthalamic…Cognitive change following deep brain stimulation in patients with movement disorders
Objective: To assess the degree and pattern of cognitive changes following Deep Brain Stimulation (DBS) in patients with Parkinson's disease (PD), Dystonia and Essential Tremor…Mild Parkinsonian signs and TIA/stroke
Objective: We aimed to determine if MPS increases TIA/stroke risk. Background: Mild Parkinsonian signs (MPS) are a syndrome of mild basal ganglia dysfunction characterized by…Dementia in Parkinson’s disease is associated with increased diffusivity in amygdala and external capsule
Objective: To identify which regions are associated with dementia in Parkinson's disease (PD) brains. Background: Dementia is common in advanced PD and its early development…Association between clinical features and pre- and post-synaptic dopaminergic dysfunction in multiple system atrophy: [18F]-FP-CIT PET and [18F]-FDG PET analyses
Objective: To investigate the correlation between clinical features and pre- and post-synaptic dopaminergic dysfunction in patients with multiple system atrophy (MSA). Background: Multiple system atrophy…Unusual phenotype of pathologically confirmed progressive supranuclear palsy with autonomic dysfunction and cerebellar ataxia
Objective: To report two cases of patients with unusual manifestation of pathologically confirmed PSP. Background: Based on the results of recent multicenter clinical-pathological studies, it…Multimodal voxel-based analysis of the infratentorial brain region in Richardson’s syndrome, progressive supranuclear palsy-parkinsonism, Parkinson variant of multiple system atrophy and Parkinson’s disease
Objective: Voxel-based analysis was applied to MRI parameters of iron content (transverse relaxation rate, R2*), microstructural integrity including mean diffusivity (MD) and fractional anisotropy (FA)…Motor features and response to levodopa in Parkinson’s disease with normal olfactory function
Objective: The aim of this study was to evaluate motor features in the OFF and ON states and the acute levodopa response in Parkinson's disease…
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