Parkinsonism-hyperpyrexia as a rare consequence of deep brain stimulator malfunction in patients with Parkinson’s disease
Objective: To report two cases of parkinsonism-hyperpyrexia secondary to failure of the deep brain stimulator (DBS) of the subthalamic nucleus (STN) in patients with Parkinson's…Programming Time and the Use of a Visualization Tool for DBS Programming of a Multiple-Source, Constant-Current System
Objective: To describe utilization of image-guided programming for use as a deep brain stimulation (DBS) planning tool during initial device programming in a cohort of…Worse Sleep Quality Aggravates the Motor and Non-Motor Symptoms in Parkinson’s Disease
Objective: The current study aims to investigate the association of sleep characteristics with motor and non-motor dysfunctions of Parkinson’s disease (PD) in a single-center, observational,…Parkinsonian disorders may have different pain features.
Objective: The aim of this study was whether the pain is a unique feature of Parkinson's disease, which precedes motor symptoms, and its characteristics would…ASYMMETRIC EARLY-ONSET PARKINSONISM DUE TO PSEN1 MUTATION
Objective: To report a novel case of early-onset parkinsonism due to a presenilin 1 gene (PSEN1) mutation. Background: Mutations in PSEN1 gene are the most…Development of C-terminal α-Synuclein Vaccine for Treatment and Prevention of Parkinson’s Disease and Other Synucleinopathies
Objective: Prothena is developing active vaccine candidates targeting α-synuclein (α-syn) epitopes shown in clinical and/or preclinical studies to disrupt synuclein pathology. These vaccines, which target…Assessment of cognitive functions and gait in PD and ET patients with pharmacoresistant tremor treated with Gamma Knife thalamotomy.
Objective: The aim of our study was to assess the impact of unilateral Gamma Knife thalamotomy on gait and balance and well as psychological functioning…Alpha-synuclein fibril-based mouse model of REM sleep behavior disorder as a prodrome of synucleinopathy
Objective: To investigate whether in wild-type mice, inoculation of α-synuclein (aSyn) preformed fibrils (PFFs) into the sublaterodorsal tegmental nucleus (SLD), a core structure associated with…Safinamide as an adjunct to Levodopa Therapy in Asian and Caucasian Patients with Parkinson’s Disease and Motor Fluctuations: A post-hoc Analysis of the SETTLE study
Objective: This study evaluated the efficacy and safety outcomes of safinamide as a levodopa adjunct therapy in Asian and Caucasian patients with Parkinson’s disease. Background:…A secretory vesicle failure in Parkinson’s disease occurs in human platelets
Objective: Since platelets use similar, if not the same, mechanisms to accumulate serotonin (5-HT) as dopaminergic neurons to store DA in their VS; we wonder…
- « Previous Page
- 1
- …
- 51
- 52
- 53
- 54
- 55
- …
- 405
- Next Page »