COMBINED CSF α-SYN RT-QuIC, CSF NFL AND MIDBRAIN-PONS PLANIMETRY IN DEGENERATIVE PARKINSONISMS: FROM BEDSIDE TO BENCH, AND BACK AGAIN
Objective: (1) to assess the combined diagnostic ability of CSF NFL, CSF RT-QuIC α-SYN and midbrain/pons MRI measures in degenerative parkinsonisms; (2) to interpret results…Contribution of external globus pallidus to motor deficits of Parkinson’s disease: optogenetic studies in murine model
Objective: The present study explored whether altered activity of external globus pallidus (GPe) neurons contributes to the development of motor deficits of Parkinson’s disease (PD).…Intensive Multimodal Rehabilitation Intervention for Moderately Advanced Parkinson’s Disease
Objective: To measure the impact of intensive multimodal neurorehabilitation in patients with moderately advanced with Parkinson’s disease (PD) Background: Dedicated neurorehabilitation is an essential part…Delayed post-stroke parkinsonism: description of two cases and possible mechanism
Objective: To present two patients who developed delayed parkinsonism years after experiencing midbrain strokes and to suggest a possible mechanism for this delayed phenomenon. Background:…Diagnostic Utility of I123-FP-CIT Single Photon Emission Computed Tomography for Patients with Clinically Uncertain Parkinsonian Syndrome
Objective: This study investigated the impact of I123-FP-CIT single photon emission computed tomography (SPECT) for the diagnosis of patients with clinically uncertain parkinsonian syndrome (CUPS)…Serum Metabolomic Characterization of PLA2G6-associated Dystonia-Parkinsonism: a case-control biomarker study
Objective: PLA2G6 is the causative gene for autosomal recessive Dystonia-Parkinsonism (PARK14). This case-control biomarker study aimed to test serum metabolomics of patients diagnosed as PARK14.…A Case of Neurodegeneration with Brain Iron Accumulation with novel Adaptor Protein-4 M1 subunit mutation
Objective: To present a patient with clinical and radiological features of neurodegeneration with brain iron accumulation (NBIA) due to a novel variant mutation in adaptor…Multi-modal MRI features and their relationship with clinical scales in Parkinson disease and Atypical Parkinsonian Syndromes
Objective: To compare MRI sings and volumetric measurements in Parkinson disease (PD), Progressive Supranuclear Palsy (PSP), and Multiple System Atrophy (MSA) and their relationship with…The Comparison of Constipation scoring system scales between Parkinson’s disease and non-Parkinson’s disease patients with constipation
Objective: This study aims to identify differences of constipation symptoms in detail by using the constipation scoring system between PD patients and non-PD patients. Background:…Real-World Outcomes Using a Novel Directional Lead from a Multicenter DBS Registry for Parkinson’s Disease
Objective: In this report, real-world outcomes using Directional Deep Brain Stimulation (DBS) Systems with multiple independent current source control (MICC) for use in managing symptoms…
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