Data-driven Subtype Classification of Patients with Early-stage Multiple System Atrophy
Objective: The objective of the present prospective study was to conduct latent class analysis (LCA) of a range of motor and nonmotor symptoms of MSA…Onset of complications in patients with Parkinson disease in Brazilian Amazon: cohort study.
Objective: To assess the onset of complications in patients with Parkinson’s disease (PD) in early stage, in a Brazilian Amazon city. Background: PD is a…Parkinsonism in individuals with genetic neurodevelopmental disorders: A systematic review
Objective: It is increasingly recognized that individuals with genetic neurodevelopmental disorders (GNDs) such as 22q11.2 deletion syndrome can suffer from parkinsonism. We aim to provide…Early Adapter: Study Protocol for the Multi-Center Post-Market Study of Adaptive Deep Brain Stimulation (aDBS) in Japan
Objective: To assess the procedures for introducing two adaptive deep brain stimulation (aDBS) modes (single and dual threshold) in Parkinson’s disease patients (PD) in a…Cellular Modeling of Tyrosine Hydroxylase Deficiency Recapitulates Patient Phenotypes and Response to Treatment.
Objective: Characterize a new cellular model of Tyrosine Hydroxylase deficiency (THD) based on induced pluripotent stem cells (iPSCs) to better understand the pathophysiology and test…Novel quantitative measures with standardised graphical tasks to objectively assess subtle changes in fine motor skill in diagnosing and monitoring of Parkinson’s disease
Objective: To integrate a handheld device with standardised graphical tasks into clinical assessment for automated objective motor symptoms rating with digital record keeping in Parkinson’s…Racial and ethnic differences in patients with Parkinson’s Disease across Parkinson’s Disease Centers of Excellence
Objective: To investigate treatment, health-related quality of life, and other outcome differences in patients with Parkinson’s Disease (PD) across race and ethnicity. Background: The inclusion…Terminal Choking in Parkinson’s Disease
Objective: To establish whether choking is a frequent cause of death in Parkinson’s Disease (PD), if this is a feared consequence of PD in patients/caregivers…Long-Term Evaluation of Deep Brain Stimulation for Treatment of Parkinson’s Disease Using a Multiple-Source, Constant-Current Rechargeable System: 4-year Follow-Up of a Prospective, Double-Blind RCT
Objective: The long-term effectiveness of a Deep Brain Stimulation (DBS) device capable of Multiple Independent Current Control (MICC) is assessed in a prospective, sham-controlled, double-blind…Benign Progressive Supranuclear Palsy: mild pathology associated with parkinsonism
Objective: Objective: To describe the clinical presentation and neuropathology of cases where the degree of tau pathology is mild, and the neuronal loss is anatomically…
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