Increased Neutrophil to Lymphocyte Ratio Distinguish Parkinson’s Disease and Parkinson Plus Syndrome
Objective: To investigate the peripheral inflammatory markers distinguishing Parkinson’s disease (PD) or Parkinson plus syndrome (PPS). Background: Previous studies had suggested that peripheral inflammation may…Delayed Osmotic Demyelination Syndrome- An Evolving Spectrum
Objective: To report a case of osmotic demyelination syndrome (ODS) with continuing clinical and radiological worsening beyond its previously established temporal course. Background: ODS is…Asymmetric midbrain atrophy in a patient with progranulin-related FTLD
Objective: We describe an atypical imaging finding in a patient with corticobasal syndrome (CBS) and a genetic diagnosis of frontotemporal lobar dementia (FTLD) associated with…Cognition in parkinson disease: Tunisian clinical experience
Objective: In this study, we identified among Parkinson Disease patients those pre-disposed to cognitive impairment, and described their clinical profiles. Background: Parkinson disease (PD) is…Parkinsonism-hyperpyrexia as a rare consequence of deep brain stimulator malfunction in patients with Parkinson’s disease
Objective: To report two cases of parkinsonism-hyperpyrexia secondary to failure of the deep brain stimulator (DBS) of the subthalamic nucleus (STN) in patients with Parkinson's…Programming Time and the Use of a Visualization Tool for DBS Programming of a Multiple-Source, Constant-Current System
Objective: To describe utilization of image-guided programming for use as a deep brain stimulation (DBS) planning tool during initial device programming in a cohort of…Worse Sleep Quality Aggravates the Motor and Non-Motor Symptoms in Parkinson’s Disease
Objective: The current study aims to investigate the association of sleep characteristics with motor and non-motor dysfunctions of Parkinson’s disease (PD) in a single-center, observational,…Parkinsonian disorders may have different pain features.
Objective: The aim of this study was whether the pain is a unique feature of Parkinson's disease, which precedes motor symptoms, and its characteristics would…ASYMMETRIC EARLY-ONSET PARKINSONISM DUE TO PSEN1 MUTATION
Objective: To report a novel case of early-onset parkinsonism due to a presenilin 1 gene (PSEN1) mutation. Background: Mutations in PSEN1 gene are the most…Development of C-terminal α-Synuclein Vaccine for Treatment and Prevention of Parkinson’s Disease and Other Synucleinopathies
Objective: Prothena is developing active vaccine candidates targeting α-synuclein (α-syn) epitopes shown in clinical and/or preclinical studies to disrupt synuclein pathology. These vaccines, which target…
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