- Parkinson’s Disease Medication Safety in the Inpatient Cohort of a Tertiary CentreObjective: Our study aimed to determine the accuracy of initial prescribing on hospital admission and the subsequent timing of administration of Parkinson’s disease (PD) medications…
- Dream enactment behavior disorder associated with pallido-nigro-luysian degeneration and tau proteinopathyObjective: To describe the detailed clinical features and pathological findings of a patient with Pallido-nigro-luysian atrophy (PNLA). Background: PNLA is a rare neurodegenerative disorder with…
- Identification of a new Homozygous mutation P.R258Q In the gene SYNJ1 of an Algerian consanguine (inbred) Family suffering from early onset atypical ParkinsonismObjective: The purpose of this observation is to demonstrate that autosomal recessive early parkinsonism is clinically and genetically heterogeneous Background: Early Onset Parkinson’s disease is…
- Dissociated longitudinal evolution of limbic serotonergic and striatal dopaminergic and serotonergic pathology in apathetic and non-apathetic patients in early Parkinson’s diseaseObjective: To investigate the longitudinal changes in striatal and extra-striatal dopaminergic and serotonergic innervation in apathetic and non-apathetic patients during the five years after the…
- Motor Function Test Protocol for Parkinsonian Triad in Rodent Model of Parkinson’s DiseaseObjective: To review motor deficits protocols and create a set of behavioural protocols that critically address the parkinsonian triad's quantification in Parkinson's disease models. Background:…
- BILATERAL SUBTHALAMIC NUCLEUS DEEP BRAIN STIMULATION IN A PATIENT WITH PARKINSON DISEASE AND INTOLERANCE TO STANDARD ANTIPARKINSONIAN DRUGS – A CASE REPORTObjective: We present a case of a 59-year-old PD patient with severe intolerance to the standard anti-Parkinsonian drugs (APDs) including levodopa (L-DOPA), MAO-B inhibitors, and…
- Physical activity and cognitive functions in individuals with Parkinson’s diseaseObjective: This study aimed to evaluate the relationship between physical activity and cognitive function in PD individuals. Background: Physical activity is positively associated with overall…
- Tele and video consultations of patients with parkinsonism in the Brazilian public health system – a real life feasibility studyObjective: To evaluate the feasibility and identify obstacles in conducting teleconsultations for patients with parkinsonism in the Brazilian public health system Background: Patients with parkinsonism…
- Effect of Venglustat by GBA Mutation Severity in Patients With Parkinson’s DiseaseObjective: Report outcomes from Part 2 of the phase 2 MOVES-PD trial (NCT02906020) in patients with PD stratified by glucocerebrosidase (GBA) gene mutation severity. Background:…
- Causes of deaths in patients with Parkinson’s disease in the era before the use of modern drug therapy and at the present timeObjective: to study the impact of modern pharmacotherapy of Parkinson's disease (PD) on the main causes of death. Background: the modern era of the use…
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