Data-driven Subtype Classification of Patients with Early-stage Multiple System Atrophy
Objective: The objective of the present prospective study was to conduct latent class analysis (LCA) of a range of motor and nonmotor symptoms of MSA…Onset of complications in patients with Parkinson disease in Brazilian Amazon: cohort study.
Objective: To assess the onset of complications in patients with Parkinson’s disease (PD) in early stage, in a Brazilian Amazon city. Background: PD is a…Parkinsonism in individuals with genetic neurodevelopmental disorders: A systematic review
Objective: It is increasingly recognized that individuals with genetic neurodevelopmental disorders (GNDs) such as 22q11.2 deletion syndrome can suffer from parkinsonism. We aim to provide…Early Adapter: Study Protocol for the Multi-Center Post-Market Study of Adaptive Deep Brain Stimulation (aDBS) in Japan
Objective: To assess the procedures for introducing two adaptive deep brain stimulation (aDBS) modes (single and dual threshold) in Parkinson’s disease patients (PD) in a…Cellular Modeling of Tyrosine Hydroxylase Deficiency Recapitulates Patient Phenotypes and Response to Treatment.
Objective: Characterize a new cellular model of Tyrosine Hydroxylase deficiency (THD) based on induced pluripotent stem cells (iPSCs) to better understand the pathophysiology and test…Novel quantitative measures with standardised graphical tasks to objectively assess subtle changes in fine motor skill in diagnosing and monitoring of Parkinson’s disease
Objective: To integrate a handheld device with standardised graphical tasks into clinical assessment for automated objective motor symptoms rating with digital record keeping in Parkinson’s…Early-onset peak dose Levodopa induced dyskinesia in elderly Ethiopian Parkinson’s disease patient
Objective: The aim was to report an early onset peak dose dyskinesia in a 55 years old Parkinson's disease patient who was naive to treatment…Characteristics of prescribers for Parkinson’s disease patients: A nationwide study on 2017 Medicare data
Objective: To assess characteristics of Medicare prescribers for Parkinson’s disease (PD) patients, as a target population for delivering advanced PD care education. Background: PD is…Characterization of pallidal neuronal activity in X-linked dystonia-parkinsonism – a model disease for compartment degeneration in the striatum
Objective: Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a highly effective symptomatic therapy for dystonia in X-linked dystonia-parkinsonism (XDP). A deeper…Evaluation of Proactive and Integrated Management and Empowerment in Parkinson’s Disease (PRIME Parkinson) in The Netherlands a prospective observational study
Objective: We will evaluate the utility of PRIME Parkinson care on a single primary endpoint (parkinsonism-related complications), which reflects the Population Health dimension, and on…
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