The Role of Simulation-Based Learning in Enhancing Clinical Skills for Managing Parkinson’s Disease in Medical Education: A Systematic Review
Objective: To evaluate the effectiveness of simulation-based learning (SBL) in enhancing clinical skills for Parkinson’s disease (PD) management among medical students and healthcare professionals. Background:…Targeted Brain Delivery of Rifampicin via PEG-PLA Nanoparticles: A Promising Therapeutic Strategy for Neuroprotection and Disease Modification in Parkinsonian Mouse Models
Objective: This study aimed to design and validate a nanoparticle-based delivery system for rifampicin, with the objective of enhancing its therapeutic efficacy, improving brain targeting,…AI-Driven Wearable Sensor Monitoring for Improved Assessment of Advanced Treatment Readiness in Parkinson’s Disease – A pilot study
Objective: This study evaluated the potential of wearables and AI-driven continuous monitoring to assess motor symptoms in Parkinson’s disease (PD). We aimed to determine their…A Systematic Review on the Reliability of Data-Driven Parkinson’s Disease Subtypes
Objective: To systematically evaluate data-driven Parkinson’s disease (PD) subtyping studies, focusing on their methodological quality and clinical applicability. Background: The heterogeneity of PD suggests distinct…Enhancing Safety and Quality of Care for Parkinson’s Disease Patients Hospitalized at a Large Academic Medical Center
Objective: To implement measures to improve quality of care in Parkinson's disease (PD) patients who are hospitalized at a large academic hospital with the goal…Addressing Sex and Gender Gaps in Parkinson’s Research: A Multi-Stakeholder Approach
Objective: To describe and address sex and gender gaps in Parkinson’s disease (PD) research through a multidisciplinary, multi-stakeholder approach that includes patient representatives, researchers, clinicians,…Gym Strength Training for People with Early Onset Parkinson’s disease
Objective: For adults living with early onset Parkinson’s disease (EOPD) to evaluate the feasibility, safety and acceptability of a gym-based resistance strength training exercise program…Effect of CUE1+ Device on Motor and Non-Motor Symptoms in Parkinson’s: A Pilot Randomised Controlled Trial.
Objective: To assess the effect CUE1+ device on motor and non-motor symptoms in people with Parkinson’s (PwP). Background: Current treatments for PwP often fail to…A Double-Blind, Cross-Over Pilot Study Comparing Adaptive Deep Brain Stimulation (aDBS) to Conventional DBS in Parkinson’s Disease
Objective: To compare the efficacy of adaptive deep brain stimulation (aDBS) to conventional DBS (cDBS) in Parkinson’s disease through a double-blind, cross-over pilot study. Background:…Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of Vent-02, a Novel CNS-Penetrant NLRP3 Inhibitor for the Treatment of Parkinson’s Disease
Objective: The objectives of this first-in-human study were to assess the safety, tolerability, pharmacokinetics (PK), food-effect and pharmacodynamics of VENT-02 in healthy volunteers Background: Vent-02…
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