Evaluating the Efficacy of Virtual Reality Simulations in Enhancing Balance Recovery Among Older Adults: A Systematic Review Using Statistical Modeling
Objective: To systematically evaluate the effectiveness of virtual reality (VR) simulations in enhancing balance recovery among older adults through statistical modeling. Background: Age-related declines in…Deep Learning-Driven Discovery of Mitochondrial Genomic Instability in Parkinson’s Disease: A Single-Cell Multi-Omics Approach
Objective: This study integrates snRNA-seq and proteomic data to (i) map mtDNA heteroplasmic mutations at single-cell resolution, (ii) identify mitochondrial-driven transcriptional dysregulation, and (iii) classify…First preliminary Experience of Tele-medicine in Deep Brain Stimulation in Middle East
Objective: Assessment of application of tele-medical DBS in patients with Parkinson's disease in Egypt and Middle East countries Background: If DBS is determined to be…Clinical validity of a digital toolkit combining active and passive assessments in early Parkinson’s Disease
Objective: We evaluated clinical validity of smartphone-administered active assessments and passive measures of motor function in early Parkinson’s Disease (PD) designed for in-home remote use.…The Impact of Non-Invasive Brain Stimulation Timing on Physiotherapy Outcomes for Parkinson’s Disease a Systematic Review with Dose-Response Analysis
Objective: To determine the best timing for non-invasive brain stimulation (NIBS) intervention to enhance physiotherapy-induced motor recovery in patients with Parkinson's disease (PwPD), and to…Caregiver and Patient perspectives on Parkinson’s Disease at tertiary, urban teaching hospital in Zambia, Africa: A Focus Group Study
Objective: Conduct focus groups to better understand the lived experience of Parkinson's Disease (PD) patients and caregivers in Zambia. Background: PD is a global neurological disease with…Sex differences in regional densities of Lewy body pathology
Objective: To assess sex differences in regional Lewy body pathology densities and their clinical correlations in cases with Lewy body (LB) pathology at autopsy. Background:…PARKinSOUND 2.0: The Impact of Orchestra Participation on Patients with Parkinson’s Disease
Objective: This study evaluates the impact of participation in a community orchestra on people with PD. Background: As interest in non-pharmacological therapies for Parkinson’s disease…Contribution of β-band functional connectivity to the α-synuclein propagation in early-stage Parkinson’s Disease: insights from the analysis of brain network properties
Objective: To investigate the relationship between CSF α-synuclein levels and EEG-based network properties, aiming to clarify their role in PD pathophysiology. Background: Parkinson’s disease (PD)…Likelihood to consent within the PREDICT-PD cohort: Identifying potential barriers or promoters of involvement in longitudinal Parkinson’s research
Objective: To establish whether age, gender or years in education influence individual likelihood to consent to Parkinson’s (PD) research. Background: Multiple factors may act as…
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