Blood derived α-synuclein seeding in the course of Parkinson’s Disease
Objective: To identify seeding capacities of soluble α-synuclein (α-syn) conformers derived from neuronal extracellular vesicles (NEs) from Parkinson´s disease (PD) patients with different disease durations…Hesperidin ameliorates rotenone-induced Parkinson’s disease in mice via improving neuroinflammation and oxidative stress
Objective: The goal of the present study is to examine the neuroprotective property of hesperidin on rotenone-induced Parkinson's disease in mice. Background: The second most…Clinical and radiological gender differences in Parkinson’s disease
Objective: To assess clinical and brain metabolic gender differences in a cohort of patients with PD Background: Many studies have elucidated gender-related clinical differences in…London-Dhaka Parkinson’s Cognition Study: A collaboration to evaluate cognitive impairment in under-represented Parkinson’s disease patients
Objective: Our aim is to study the prevalence of cognitive impairment (CI) in a diverse group of people with Parkinson's disease (PwP) from East London,…motor and non-motor correlates of hyposmia detected by the italian olfactory identification test (ioit) in an italian cohort of parkinson’s disease patients
Objective: To characterize olfaction in a cohort of PD patients and to investigate the relationship between olfactory impairment with both motor and non-motor features and other clinical characteristics…MR-morphological changes in PD patients with heterozygous GBA mutation
Objective: This study investigates possible cerebral morphological differences between GBA-gene-mutation carriers with Parkinson´s disease (PD) and PD-patients without GBA-gene-mutation depending on in- or exclusion of…Parkinson’s disease and Charcot-Marie-Tooth type 2: coincidental or causal?
Objective: To report a patient with Charcot-Marie-Tooth (CMT) type 2N (CMT2N) due to AARS gene mutation who developed early-onset Parkinson’s disease (PD). Background: Aminoacyl tRNA…Optimal topographic characteristics of focused ultrasound unilateral thalamotomy for tremor-dominant Parkinson´s disease
Objective: To define topography that correlates with tremor control after unilateral focused ultrasound (FUS) thalamotomy for tremor-dominant Parkinson´s Disease (TDPD). Background: Unilateral FUS thalamotomy of…Parkinson’s disease management in the community
Objective: To explore perceptions of people with Parkinson's disease and family carers about the use and impact of health and social care services, community and…Exome-wide contribution of ultra-rare variants to the genetic architecture of Parkinson’s disease and Cutaneous Malignant Melanoma
Objective: To analyze the UKBiobank cohorts of Parkinson’s disease (PD) and Cutaneous Malignant Melanoma to uncover shared genetic factors explained by ultra-rare damaging coding variants…
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