Association Between Cerebral Glucose Metabolism and Amyloid Deposition in Parkinson’s Disease
Objective: To investigate the potential association between cerebral amyloid (Aβ) deposition and regional brain metabolism in patients with Parkinson's disease (PD) Background: Although Parkinson's disease (PD)…Comparative Study of Whole-Brain Functional Connectivity Patterns in Parkinson’s Disease and Essential Tremor: A Resting-State fMRI Study
Objective: Our study aimed to analyze the alterations in brain FC in subjects with tremor-dominant PD compared to ET subjects. Background: While both tremor-dominant Parkinson’s…The Impact of Bilateral STN- Deep Brain Stimulation on Motor Symptoms and Quality Of Life in Advanced Parkinson’s Disease: A Single Center’s Experience
Objective: The aim of this study was to examine the effects of bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) on motor symptoms and quality…Ethnic and Gender Disparities in Access to Deep Brain Stimulation: A Qualitative Exploration
Objective: The objective of this qualitative inquiry is to explore the experiences of people with movement disorders in terms of ethnic and gender-related barriers to…A comparative study of focused ultrasound unilateral thalamotomy and subthalamotomy for medication refractory Parkinsonian tremor
Objective: Unilateral focused ultrasound (FUS) thalamotomy of the ventral intermediate thalamic nucleus (FUS-Vim) is effective in treating Parkinson’s disease (PD) tremor. FUS ablation of the…Can Technology Improve Service Delivery and Patient Outcomes in a Parkinson’s Speech and Language Therapy Clinic?
Objective: - Determine if Telea, an online care platform, can aid in efficiently addressing caseload needs and quantify clinical time saved through…Developing Composite Digital Measures for Tracking Parkinson’s Disease (PD) Progression using a Comprehensive Machine Learning-based Framework
Objective: To develop composite digital measures that could be used to track disease progression in early PD patients, and to determine whether they can outperform…Unlocking Movement Disorder Specialist Capacity and Mitigating Risk: a Platform Solution for Cost Reduction and Care Optimization in Parkinson’s Disease
Objective: Improve patient and physician care delivery experience through a technology-driven coaching and triage system. Background: Limited worldwide supply of Parkinson’s specialty care restricts access…A Device Agnostic Pipeline for Gait Detection and Assessment in Free-living and Clinical Environments
Objective: To provide a framework for a device agnostic gait analytics pipeline for standardizing and improving quantitative gait analysis using wearable sensors. Background: Gait impairments…GBA1 deficiency differentially affects endolysosomal trafficking in neurons and astrocytes
Objective: To characterize how GBA1 deficiency alters endolysosomal trafficking in astrocytes versus neurons. Background: Mutations in the gene glucosidase, beta acid 1 (GBA1) not only increase risk…
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