Impaired Speech Perception in Noise (SPiN), Hearing Loss, and Cholinergic Denervation in Parkinson’s Disease
Objective: This study will investigate the relationships among speech-perception-in-noise (SPiN), hearing acuity, and cholinergic system changes in patients with PD. Background: Recent studies highlight a…Fatty Acid Metabolic Reprogramming Regulates Glial-Epithelial Axis via Nur77 Palmitoylation in Intestinal Dysfunction in Parkinson’s Disease
Objective: This study aims to elucidate the regulatory role of stearoyl-CoA desaturase 1 (SCD1) in Parkinson’s disease (PD)-associated intestinal dysfunction, focusing on its mechanism in…Transcranial sonography in Parkinson’s disease patients
Objective: To present the usage and results of transcranial sonography (TCS) in Parkinson's disease (PD) patients. Background: (TCS) has emerged as a valuable diagnostic tool…Exploring local gyrification index to understand Parkinson’s disease with mild cognitive impairment
Objective: To investigate correlations between local gyrification index (LGI) and neuropsychological variables in participants with Parkinson's disease (PD) experiencing mild cognitive impairment (PD-MCI). Background: PD…Cholinergic activity associates with cognitive function in PD using [18F]VAT
Objective: To map the relationship between cholinergic activity in Parkinson Disease (PD) and cognitive performance and identify any differences in this relationship in cognitive impairment.…Sex-Dependent Associations Between PGLYRP2 Variants and Parkinson’s Disease Across Diverse Ancestries
Objective: To investigate the association between PGLYRP2 polymorphisms and Parkinson’s disease (PD) across diverse ancestral populations. Background: Emerging evidence suggests a role of the gastrointestinal…Analysis of LRRK2 Exonic Variants in Parkinson’s Disease in Chinese Population
Objective: To investigate the frequency of multiple LRRK2 variants in Parkinson's disease (PD) cohort, and to explore the effect of LRRK2 variants on the occurrence…Gene Polymorphisms of Parkinson’s Disease risk locus and idiopathic REM Sleep Behavior Disorder
Objective: Genetic factors play an important role in idiopathic rapid eye movement sleep behavior disorder (iRBD) but have not been fully studied. Background: This study…Rare Variants in RAB GTPases in Parkinson’s Disease
Objective: To investigate variants across the RAB GTPase genes in Parkinson’s disease (PD). Background: The Global Parkinson’s Genetics Program (GP2, http://gp2.org/) is an international collaborative…Applying growth mixture models to elucidate heterogeneous trajectories of cognitive change in Parkinson’s Disease
Objective: To apply growth mixture models (GMM) to elucidate heterogeneity in cognitive change trajectories in Parkinson’s Disease (PD) among idiopathic PD (iPD), GBA1, and LRRK2…
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