Systematic mapping of Parkinson’s disease gene interactions
Objective: Here, we aim to identify functional interactions between the Parkinson’s disease-associated genes. Background: Understanding how genes interact to produce a given phenotype is a…Molecular alterations and pathological remodeling of colonic wall in patients with Parkinson’s disease
Objective: To evaluate, in an integrated manner, changes in faecal microbiota composition, morpho-functional alterations of the colonic mucosal barrier and changes of inflammatory markers in…Sleep stability, arousals and cycle structure in alfa-synucleinopathies: a comparative study between isolated REM sleep behaviour disorder (iRBD), Parkinson’s Disease (PD) and Dementia with Lewy Bodies (DLB)
Objective: To compare sleep stability, arousals and sleep cycle structure between two sets of diagnosis: iRBD vs PD vs DLB; patients with RBD (RBD+) vs…Intermuscular coherence as a biomarker of subthalamic nucleus deep brain stimulation efficacy in Parkinson’s disease
Objective: Deep brain stimulation of the subthalamic nucleus (STN-DBS) is an established treatment in advanced Parkinson’s disease (PD). However, the clinical outcome after STN-DBS is…Frequency of non-motor symptoms in GBA-PD may differ in carriers of mild vs. severe pathogenic variants
Objective: Parkinson's disease (PD) patients with pathogenic variants in the GBA (glucocerebrosidase) gene (GBA-PD) were reported to exhibit a younger age at onset, faster progression…LFP beta frequency OFF-ON shift in subthalamic nucleus in Parkinson’s disease
Objective: The aim of the current study is to investigate the frequency characteristics of beta activity in Parkinson’s disease. We hypothesized that beta peak central…Video-oculographic biomarkers for evaluating vertical ocular dysfunction in progressive supranuclear palsy
Objective: Objective: PSP patients typically show reduced amplitude and velocity of vertical saccades, but saccadic abnormalities have also been reported in PD. We investigated the…Levodopa-carbidopa intestinal gel infusion and long-term tolerability in Parkinson’s: multicentre, international 13-year follow-up data
Objective: To evaluate the long-term range and nature of Levodopa-carbidopa intestinal gel (LCIG) infusion-related complications in people with Parkinson’s (PwP). Background: LCIG infusion is an…EEG power-spectra parametrization and cognitive ability in Parkinson’s disease
Objective: To parametrize EEG power-spectra and examine the association of periodic and aperiodic components with cognitive ability in Parkinson's disease (PD). Background: PD is associated…At-home prolonged adaptive deep brain stimulation improves symptoms and reduces side effects in Parkinson’s disease
Objective: Objective: To assess the effect of at-home adaptive deep brain stimulation (aDBS) on symptoms and treatment-associated side-effects in one patient with Parkinson’s disease (PD),…
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