A Novel Dopaminergic Modulator (NDM-101) as an Adjunct to Levodopa: Enhancing Motor Control Without Worsening Dyskinesia in Parkinson’s Disease
Objective: To evaluate the efficacy and safety of NDM-101 as an adjunct to levodopa in reducing OFF-time, improving motor function, and maintaining quality of life…AI-Driven Prediction Models for Advanced Parkinson’s Disease: A Data-Driven Approach Using PPMI and CDEPA Criteria
Objective: To develop machine learning models that predict advanced Parkinson’s disease (APD) by integrating quantitative clinical data from the Parkinson’s Progression Markers Initiative (PPMI) with…Hospitalization Safety in Parkinson’s Disease (PD): Baseline Outcomes Tracked over 1 Year and a Multi-disciplinary Program to Improve Care
Objective: To report baseline hospitalization outcomes in PD and the development of a comprehensive program for quality improvement. Background: Hospitalization is common in PD and…Improving Guitar Strumming Mechanics in Parkinson’s Disease: A Case Series Using a Forearm Stabilization Device
Objective: This case series aims to explore the potential benefits of a guitar adaptation in enhancing mechanics of guitar strumming among this patient sample. Specifically,…Noise assessment acoustic measures of sustained vowel in patients with Parkinson’s disease
Objective: To investigate and quantify the presence of noise in the vocal signals of Parkinson's disease (PD) patients and healthy volunteers (HV) using acoustic measures,…Advancing the Quality of Life of Parkinson’s Disease (PD) Patients in Ethiopia: The Impact of Self-Management and Coping Skills Training Programs on Patients in a Resource Constrained Settings
Objective: Evaluating the effectiveness of training in self-management and coping skills for patients with PD Background: The Parkinson’s Patients Support Organization Ethiopia (PPSO-E) implemented a…Impact of Gastrointestinal Dysfunction Symptoms on Psychomotor Recovery Following 8-Week Aerobic Interval Training in Parkinson’s Disease – Preliminary Results
Objective: To investigate the impact of gastrointestinal dysfunction symptoms (GIDS) on psychomotor recovery following 8-week aerobic interval training (AIT) in Parkinson's disease (PD). Background: GIDS…Impact of ND0612 on Levodopa-Induced Dyskinesia in Parkinson’s Disease: Post hoc Analyses From a Randomized, Active-Controlled Study
Objective: To evaluate dyskinesia-related outcomes between optimized subcutaneously administered levodopa/carbidopa (ND0612) + immediate-release levodopa/carbidopa (IR-LD/CD) vs optimized oral IR-LD/CD in patients with Parkinson’s disease (PD).…Development and Validation of Personal Technology to Treat Hypophonia in Patients with Parkinson’s Disease
Objective: The purpose of this study was to develop and validate wearable technology to improve vocal intensity in patients with Parkinson’s Disease. Background: Parkinson’s disease…Increased “Off” Time Is Associated With Poorer Clinical and Humanistic Outcomes in Patients With Advancing Parkinson’s Disease: Results From the PROSPECT Observational Study
Objective: To evaluate the association of increased “Off” time with clinical and humanistic outcomes in people with advanced Parkinson’s disease (PwP) inadequately managed by oral…
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