Adult hippocampal neurogenesis-associated memory performance in people with Parkinson’s disease with and without cognitive impairment
Objective: To evaluate the role of adult hippocampal neurogenesis (AHN)-associated memory measures to the cognitive performance of people with Parkinson’s disease (PwP) with or without…Improvement of short-term satisfaction with life and treatment in Parkinson´s disease after subthalamic stimulation
Objective: The main aim of this study was to test the hypothesis that STN-DBS improves satisfaction with life and treatment in PD. Background: Subthalamic stimulation…A framework to standardize gait study protocols in Parkinson’s disease
Objective: To provide recommendations for a minimum set of gait outcome measures to be adopted in projects evaluating people with Parkinson’s disease (PD). Background: Gait…Postoperative change of local field potentials of subthalamic nucleus during and after period of microlesion effect of implantation of deep brain stimulation lead.
Objective: To study changes in beta oscillation before and after microlesion effect in deep brain stimulation (DBS) lead implantation. Background: Increased beta oscillation has been…Inhibition of LRRK2 kinase activity promotes glucocerebrosidase transport to the lysosomes in primary monocyte-derived macrophages from patients with GBA-associated Parkinson’s disease
Objective: The aim was to evaluate the effectiveness of leucine-rich repeat kinase 2 (LRRK2) kinase activity inhibition in restoring transport of the enzyme glucocerebrosidase (GCase),…Wavelet-based bracketing, time-frequency beta-burst detection: new insights in Parkinson’s disease
Objective: To identify bursts in wide frequency bands and show the relation between burst features and clinical scores. Background: Beta burst activity is a pathophysiological…Exploring patient-physician communication in Parkinson’s disease management: a qualitative analysis
Objective: To explore the unmet needs in patient-physician communication from different perspective.To explore the unmet needs in patient-physician communication from different perspective. Background: Patient-physician communication…Neuroprotective properties of arylpiperazine-sulphonamides in an in vitro model of Parkinson’s disease
Objective: To investigate the neuroprotective effects of novel arylpiperazine compounds as measured by viability of SH-SY5Y cells in vitro. Background: Parkinson’s disease (PD) is a…Continuous subcutaneous levodopa/carbidopa infusion with ND0612 for patients with Parkinson’s disease and motor fluctuations: Results from the Phase 3 randomized, active-controlled BouNDless study
Objective: Determine the efficacy, safety, and tolerability of ND0612 versus oral immediate-release levodopa/carbidopa (IR-LD/CD) in people with Parkinson’s disease (PwP) experiencing motor fluctuations. Background: ND0612…Safety assessment of pimavanserin in Parkinson’s disease psychosis patients: Evidence from a systematic review and meta-analysis of randomized controlled trials
Objective: This systematic review and meta-analysis aimed to assess the safety profile of pimavanserin in Parkinson’s disease psychosis (PDP) patients from the available randomized controlled…
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