Brain activity of the emotional circuit in Parkinson’s disease patients with freezing of gait
Objective: The aim of this observational study was to assess brain functional MRI (fMRI) activity during a “FoG observation task” in PD-FoG patients relative to…A combined imaging based biomarker for Parkinson’s disease using diffusion kurtosis and quantitative susceptibility mapping
Objective: We aimed to investigate the utility of combined quantitative susceptibility mapping (QSM) and diffusion kurtosis imaging (DKI) as complementary tools in characterizing pathological changes…Movement vigor is differentially encoded in motor cortex and globus pallidus in Parkinson disease
Objective: To test the hypothesis that pallidocortical local field potential (LFP) beta oscillations encode movement vigor. Background: Recent work suggests the motor basal ganglia adjusts…Effects of Levodopa-Carbidopa Intestinal Gel on Dyskinesia and Non-Motor Symptoms including Sleep: Results from a Meta-Analysis with 24-month follow-up
Objective: To evaluate the impact of levodopa-carbidopa intestinal gel (LCIG) on dyskinesia, sleep, and other non-motor symptoms over 24 months after initiation. Background: Complications of…Evaluating the Relationship between Apathy and Grit as it Relates to Participation in a Community Exercise Program in the Population with Parkinson’s Disease.
Objective: The primary aim of this study was to explore the relationship between apathy levels of the PD individual and apathy levels of their caregiver.…Mobile application for assessing the likelihood of developing depression in patients with Parkinson’s disease
Objective: To develop a mobile application for assessing the likelihood of developing depression in patients with Parkinson's disease (PwPD), taking into account the number of…Serial olfactory testing for the diagnosis of prodromal Parkinson disease in the Parkinson Associated Risk Syndrome (PARS) study
Objective: To assess whether repeat olfactory testing in initially hyposmic subjects improves prediction of conversion to Parkinson disease (PD). Background: Hyposmia is a common prodromal…GBA Mutation Accumulates Higher Alpha-Synuclein in Alpha-Synucleinopathies
Objective: To investigate whether post-translational modifications of α-synuclein will give rise to species that differ between PD cases with N370S GBA mutation and WT-PD. Background:…Effect of COVID-19 stressors on mental health and quality of life in Parkinson’s disease
Objective: To investigate subgroup differences in the effect of COVID-19 stressors on mental health and quality of life in people with Parkinson’s disease. Background: In…A usability study of an exergame application for Parkinson’s disease
Objective: To create and test the usability of a smart device-based application that delivers a gamified exercise session specifically designed for people with early Parkinson’s…
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