Long-term outcome of adaptive DBS using LFP sensing technology
Objective: The aim of this study was to clarify the long-term outcome of Parkinson’s disease patients receiving STN-DBS with adaptive DBS setting. Background: It has…The anti-alpha-synuclein antibody Lu AF82422 was safe and well tolerated in a FIH-SAD study in healthy subjects and patients with PD
Objective: Evaluation of safety, tolerability, pharmacokinetics (PK) and target engagement (TE) in healthy subjects (HS) and patients with Parkinson’s disease (PD) following single ascending doses…The anti-alpha-synuclein antibody Lu AF82422 binds to pathological alpha-synuclein species from human brains and inhibits seeded alpha-synuclein aggregation
Objective: Lu AF82422 is a human IgG1 monoclonal antibody that binds all known forms of alpha-synuclein (aSyn), including monomeric, aggregated and truncated. Data are presented…Evaluation of the association between total electrical energy delivered (TEED) and cognitive function six months after DBS in patients with Parkinson’s disease
Objective: We aimed to investigate the neuropsychological outcome six months after bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkison's disease (PD) patients and…Caregiver’s burden in Parkinson’s disease: A mixed methods study
Objective: This study had a two-fold aim: (i) to assess how characteristics of informal caregivers and people with PD affect caregiver burden and (ii) to…Pressure Sensor Insole Gait Assessment for Parkinson’s Disease patients: A pilot study
Objective: To assess the correlations between gait characteristics obtained from pressure sensor insoles, and clinical assessments of motor features in Parkinson’s Disease (PD) patients. Background:…Feasibility and efficacy of a multidisciplinary home-telehealth intervention program to reduce falls and improve quality of life in Parkinson´s disease. First results.
Objective: To evaluate the results of feasibility and effectiveness of multidisciplinary home-telehealth intervention program to reduce falls and improve quality of life in patients with…Fear of progression is predicted by anxiety and self-efficacy but not disease-specific parameters in patients with Parkinson’s disease: data from a multicenter cross-sectional study
Objective: To examine Fear of progression (FoP) prevalence and to analyze FoP predictors in a large Parkinson’s disease (PD) sample. Background: FoP is a reactive…The results of DBS in patients with Parkinson’s disease for 10 years in Belarus
Objective: To study the efficiency and SE of DBS in PD patients in Republican Research and Clinical Center of Neurology and Neurosurgery in Belarus for…Optimization of a neuromelanin MRI protocol for use in a longitudinal study of substantia nigra depigmentation in early Parkinson’s Disease (the InsIght-PD study)
Objective: To optimize a neuromelanin-MRI (NM-MRI) protocol for robust and timely change analysis; and acquire serial NM-MRI data in controls and early Parkinson’s Disease (PD),…
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