CCL5 promotes Th17 migrating into SNpc by promoting Th17 proportion increase and LFA-1 expression
Objective: To explore the specific pathway by which CCL5 induces Th17 cells migrating into substantia nigra pars compacta (SNpc) to aggravate Parkinson's disease (PD). Background:…Blood-derived α-synuclein from Parkinson´s disease patients is able to seed pathology
Objective: To identify seeding capacities of soluble α-synuclein (α-syn) conformers derived from neuronal extracellular vesicles (NEs) from Parkinson´s disease (PD) patients. Background: PD pathology is…Characteristics and Techniques to Improve Micrographia in Parkinson’s Disease
Objective: To analyze and identify the characteristics found in micrographia and provide methods of improving the symptom. Background: Micrographia, also known as small handwriting, is…Do clinical neuropsychological tasks capture visuoperceptual deficits in culturally-diverse individuals with Parkinson’s disease and hallucinations?
Objective: To explore whether the Judgement of Line Orientation (JLO), VOSP Silhouettes, and VOSP Object Decision tasks distinguish performance of individuals with Parkinson’s Disease (PD)…DIFFERENT PATTERNS OF ACUTE SACCADIC RESPONSES TO LEVODOPA CHALLENGE TEST IN DE NOVO PARKINSON’S DISEASE: POSSIBILE PROGNOSTIC IMPLICATIONS
Objective: To explore possible different patterns of acute saccadic responses to Levodopa Challenge Test (LCT) in a de novo drug-naïve Parkinson’s Disease (PD) population and…Increased Neutrophil to Lymphocyte Ratio Distinguish Parkinson’s Disease and Parkinson Plus Syndrome
Objective: To investigate the peripheral inflammatory markers distinguishing Parkinson’s disease (PD) or Parkinson plus syndrome (PPS). Background: Previous studies had suggested that peripheral inflammation may…Sweetspot analysis of Deep Brain Stimulation in Parkinson´s disease: Beyond the subthalamic nucleus?
Objective: To study the relationships between clinical response and leads location -in a cohort of Parkinson’s disease (PD) patients and deep brain stimulation of subthalamic…Impact of two different rechargeable pulse generators on parkinsonian patients with deep brain stimulation
Objective: This study compared the recharging frequency and duration, perceived impact and self-management of recharging, and motor symptom suppression in fifteen PD patients who underwent…Exploring the morning akinesia in Parkinson’s disease with the wearable sensor STAT-ON
Objective: To detect the morning akinesia (MA) through the analysis of the gait fluidity (GF) measured by the sensor STAT-ON. Background: The STAT-ON sensor's detection…What is the appropriate sleep position for Parkinson’s disease patients with orthostatic hypotension in the morning?
Objective: To determine the effect of sleep positions on morning OH in PD patients Background: Orthostatic hypotension (OH) is considered one of the most disabling…
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