Clinical presentation of SNCA Duplication Parkinsonism in a Family Kindred
Objective: To report phenotype variability in a family with SNCA duplication associated Parkinsonism. Background: Pathogenic variants in SNCA, the gene coding for α-synuclein, cause familial…Preliminary estimates of the effects of deep brain stimulation on gait kinematics in Parkinson disease and essential tremor.
Objective: To determine the change in gait parameters following deep brain stimulation (DBS) in Parkinson disease (PD) and essential tremor (ET). Background: DBS is an…Deep Learning Approaches for Recognition of Parkinson’s Disease Patients through Handwriting, Audio and Video Analysis
Objective: The aim of this study was to build PD diagnostic models based on deep learning approaches using technologies including handwriting identification, automatic speech recognition…Plasma p-tau181, neurofilament light chain and association with cognition in Parkinson’s disease
Objective: To investigate the association of plasma p-tau181 and NfL with cognitive performance and cognitive progression in PD patients. Background: Cognitive impairment (CI) is a…Machine learning algorithms for classification and analysis of pen-on-paper Archimedes spirals
Objective: To classify tremor syndromes from freely hand drawn pen-on-paper Archimedes spirals using classical machine learning techniques. Background: Spiral drawings (Archimedean) are commonly used in…Classical Machine Learning approaches to automate tremor detection from electrophysiological data
Objective: To detect tremor syndromes from electrophysiological signatures using classical machine learning techniques. Background: Electromyographic recordings combined with accelerometry data are widely used to measure…The relationship of non-motor symptoms in Parkinson’s disease
Objective: Evaluation of non-motor symptoms in patients with Parkinson's disease, evaluation of the relationship of autonomic and neuropsychiatric disorders. Background: This work included a comprehensive…Cerebro-cerebellar motor networks in clinical subtypes of Parkinson’s disease
Objective: This study investigated functional alterations within the cerebro-cerebellar system in tremor-dominant (TD) and postural-instability-and-gait-disorder (PIGD) subtypes of Parkinson’s disease (PD) using stepwise functional connectivity…The reasons for referral to a Parkinson’s Clinical Psychology service
Objective: To understand the reasons for referral to a Parkinson's Clinical Psychology service. Background: In recent times, the psychological impact of Parkinson’s Disease has become…Apomorphine Sublingual Film Versus Subcutaneous Apomorphine in the Treatment of OFF Episodes in Parkinson’s Disease: Results From an Assessment of Patient Satisfaction
Objective: Evaluate treatment satisfaction with apomorphine sublingual film (SL-APO) vs subcutaneous apomorphine (SC-APO) for the treatment of OFF episodes in patients with Parkinson’s disease (PD).…
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