Trans-Spinal Theta Burst Magnetic Stimulation Enhances Treadmill Training Effects on Gait in Parkinson’s Disease
Objective: To investigate whether intermittent Theta Burst Trans Spinal Magnetic Stimulation(iTB–TsMS) enhance treadmill training benefit on gait function, freezing of gait(FoG), other motor symptoms and…A retrospective study on thyroid dysfunction mimicking Parkinsonian symptoms
Objective: This retrospective study analyzes outcomes of nine patients (three females, six males) admitted to the endocrinology department from 2020 to 2024. Initially diagnosed with…Effect of Continuous Subcutaneous Infusion of Foslevodopa/Foscarbidopa on motor fluctuations, dyskinesia, and sleep; subjective vs. PKG watch recordings.
Objective: To evaluate the impact of continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa on bradykinesia, dyskinesia, and sleep quality using self-reported Hauser diaries and Parkinson’s KinetiGraph…Trihexyphenidyl as a Treatment for Severe Freezing of Gait in Parkinson’s Disease: A Case Report
Objective: To present a unique case in which trihexyphenidyl was used as an effective treatment to dramatically reduce freezing of gait (FoG) in a Parkinson’s…Zonisamide for Motor Symptoms and OFF-Time Reduction in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Objective: To evaluate the efficacy and safety of zonisamide as an adjunct therapy for improving motor function and reducing OFF-time in patients with Parkinson’s disease…Efficacy and Safety of Nicotine in Parkinson’s Disease: A Systematic Review and Meta-analysis
Objective: This systematic review and meta-analysis aimed to evaluate the safety and efficacy of nicotine compared with placebo in the treatment of Parkinson’s disease (PD).…The sphingolipid Lyso-Gb3, a biomarker for the lysosomal storage disorder Fabry Disease, is significantly elevated in blood from patients with Parkinson’s Disease
Objective: To better understand lysosomal dysfunction in Parkinson’s Disease. Background: Lysosomal dysfunction and α-synuclein accumulation play central roles in Parkinson’s Disease. They are interconnected by…Metabolomic breath landscape analysis unravels lipid biomarker candidates in patients with monogenic and idiopathic Parkinson’s disease
Objective: We propose an untargeted metabolomics approach using exhaled breath analysis to (1) characterize the non-volatile metabolomic breath signature of Parkinson’s disease (PD) patients with…Blood and CSF Biomarkers of Cognitive Impairment in Alpha Synucleinopathies
Objective: The aim was to investigate the role of both well-established and novel protein biomarkers of cognitive impairment in Parkinson’s disease (PD) and multiple system…Analyzing Longitudinal Correlation Between CSF Tau, Alpha-Synuclein, and Dysautonomia in Parkinson’s Disease Over Five Years
Objective: To examine the longitudinal association between tau, alpha-synuclein, and dysautonomia in Parkinson’s disease (PD). Background: PD is characterized by dopaminergic neural loss [1] and…
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