Relationships Between Preferred Walking Speed and Accelerations at the Head and Trunk in Individuals with Parkinson’s Disease (PD) and Healthy Elderly
Objective: To assess the relationship between head and trunk accelerations and the preferred walking speed (PWS) in individuals with and without PD Background: Bradykinesia and…Prospective observational study on the effects of physical exercise and lifestyle modifications in patients with Parkinson’s disease
Objective: This study aimed to assess the effectiveness of physical activity, which includes all movements that increase energy expenditure, in conjunction with exercise, characterized as…Clinicians’ Views on the Use of a Patient Decision Aid for DBS in Parkinson’s Disease
Objective: To assess neurologists’ awareness of, and experience using, patient decision aids. Background: Patients with Parkinson’s disease (PD), their caregivers, and medical teams encounter numerous…Longitudinal Analysis of BRAIN test in isolated REM sleep behaviour disorder with and without hyposmia.
Objective: To assess motor dysfunction in individuals with polysomnography (PSG)-confirmed isolated REM Sleep Behaviour Disorder (iRBD), self-reported RBD (sRBD), and sRBD with smell loss (hyposmia).…Pharmacokinetic Analysis of Subcutaneous Levodopa/Carbidopa Delivery With ND0612
Objective: To (i) use a population pharmacokinetic (PK) model to compare predicted levodopa PK parameters when levodopa is delivered as investigational ND0612, as oral immediate-release…Risk of Motor Complications in Early Parkinson’s Disease Patients Treated with Opicapone in the EPSILON study: Effect of Levodopa Dose
Objective: This post-hoc analysis of the EPSILON study evaluated whether levodopa dose (<400mg/day vs. ≥400mg/day) and opicapone (OPC) timing (at double-blind [DB] or open-label extension…Continuous Subcutaneous Apomorphine Infusion (CSAI) Reduces OFF Periods and Extends Periods of GOOD ON Time: Heatmap Analysis of the TOLEDO Study
Objective: Use heatmap analysis to quantify and examine diurnal patterns of OFF and GOOD ON time periods throughout the day, and changes in the number…Efficacy of ND0612 in Patients at Different Stages of Disease Severity: Subgroup-Analyses From a Randomized, Active-Controlled Study in People With Parkinson’s Disease Experiencing Motor Fluctuations
Objective: To evaluate the efficacy of investigational ND0612 in reducing motor fluctuations in patients with Parkinson’s disease (PD) at different stages of disease and/or symptom…Adaptive Deep Brain Stimulation for Parkinson’s Disease in Routine Clinical Care: First Experiences
Objective: To describe the treatment process and outcomes of the first patients with Parkinson’s disease (PD) treated with adaptive DBS (aDBS) within routine clinical care…Safety, Tolerability, and Preliminary Efficacy of NouvNeu001 for the Treatment of Advanced Parkinson’s Disease: A Multi-center, Open Label, Phase 1 Study
Objective: This Phase 1 study aims to evaluate the safety, tolerability, preliminary efficacy, and optimal dose of NouvNeu001 for treating mid to late-stage Parkinson’s disease…
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