Gut Microbial Metabolites and Future Risk of Parkinson’s Disease: A Metabolome-wide Association Study
Objective: To prospectively investigate the association between plasma microbial metabolites and Parkinson’s disease (PD) risk within a metabolomics framework. Background: Gut microbiota is altered in…A Machine Learning Approach for Early Identification of Prodromal Parkinson’s Disease
Objective: The aim of this project is to analyze available data of voice, Tappy keystroke, spiral drawings, and gait sample data involving PD patients and…First in vivo evidence of the role of the noradrenergic system in olfactory dysfunction in Parkinson’s disease
Objective: To investigate the relationship between in vivo noradrenergic markers and olfactory impairment in patients with Parkinson’s disease (PD). Background: Degeneration of the noradrenergic (NA)…Dopamine Transporter Imaging as Monitoring Biomarker in Parkinson’s Disease
Objective: To investigate the longitudinal relationship between changes in dopamine transporter single-photon emission computed tomography (DaT SPECT) and changes in motor symptom severity in Parkinson’s…Data-driven image-based subtyping and staging of neurodegeneration in Parkinson’s disease
Objective: We aimed to conduct image-based, data-driven classification of Parkinson’s disease (PD) progression using event-based modeling (EBM) and derive neuropathological insights from the results. Background:…Characterizing levodopa-induced dyskinesias using multimodal neuroimaging, clinical and behavioral measures
Objective: Our objective is to investigate potential differential modulation in motor and executive function networks among patients with LID, and to explore its correlation with…Clinical Trends and Clinician Perceptions Regarding Asleep and Awake DBS
Objective: To determine trends and perceptions regarding Asleep and Awake Deep Brain Stimulation (DBS) in the USA and abroad. Background: DBS clinical practice continues to…Deep Brain Stimulation Complications in Parkinson’s Disease Patients: A 15-year Single-Centre Review
Objective: This study aims to identify the complications of subthalamic nucleus (STN) deep brain stimulation (DBS) in patients with advanced Parkinson’s disease (PD) to direct…Clinical and Imaging Changes in Parkinson’s Disease Patients Under Spinal Cord Stimulation: A Double Blinded Analysis
Objective: Evaluate clinical and biomarker changes from spinal cord stimulation (SCS) in Parkinsons Disease (PD) under sham controlled randomized evaluation. Background: SCS has been proposed…Risk Tolerance of Therapeutic Interventions in People with Parkinson’s Disease
Objective: To determine the sociodemographic factors of people with Parkinson’s disease (PD) associated with risk tolerance when considering interventions. Background: Gender and racial disparities in…
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