Comparative Efficacy and Safety of Opicapone in Parkinson’s Disease: An Updated Systematic Review and Meta-Analysis
Objective: To evaluate the efficacy and safety of Opicapone drug in patients with Parkinson’s disease (PD) using an updated systematic review and meta-analysis, including newly published randomized controlled trials…Single- and Multi-Unit Activity in STN Provides Enhanced Insight into Speech-Related Neural Dynamics in Parkinson’s Patients
Objective: We aimed to elucidate neural representations in local field potentials (LFP) and single- and multi-unit activity of subthalamic nucleus (STN) neurons during speech tasks,…Blood-based biomarkers for diagnosis and prediction of Parkinson’s Disease in GBA1 individuals
Objective: To investigate glucocerebrosidase (GCase) enzymatic activity and different forms of α-synuclein (aggregated -Asyna – and monomeric - Asynm) in peripheral blood mononuclear cells (PBMCs)…Distinct Peripheral Immune Profiles of Parkinson’s Disease and Multiple System Atrophy
Objective: We aimed to compare peripheral blood mononuclear cell (PBMC) subsets between Parkinson’s disease (PD) and multiple system atrophy (MSA) to identify disease-specific immune signatures…Plasma P-tau217 detects Alzheimer’s co-pathology and predicts cognitive decline in Parkinson’s disease
Objective: The objectives of this study are to compare plasma phosphorylated tau-217 (P-tau217) levels in Parkinson’s disease (PD) with versus without Alzheimer’s disease (AD) copathology…Association of periodontal pathogen with subtypes of motor symptoms of Parkinson’s disease
Objective: This study aimed to investigate the relationship between the relative abundance of periodontal pathogens in tongue-coating samples and clinical factors in patients with Parkinson’s…Baseline brain inflammation is associated with less cognitive progression at 24 months in subjects with de novo Parkinson’s disease
Objective: To examine if brain inflammation measured by 18F-DPA-714 imaging is associated with cognitive change in subjects with early Parkinson’s disease (PD). Background: Evidence for…GPi Lesioning vs. DBS: Does Targeting the Same Structure Differently Affect Cognition in Parkinson’s Disease?
Objective: To compare the cognitive and quality of life (QoL) outcomes of GPi-DBS and GPi-RF, investigating whether lesion-based approaches pose a greater cognitive burden over…Negative Correlation Between Apathy and Performance on Memory Tasks in Patients with Idiopathic Parkinson’s Disease without Dementia.
Objective: To establish the impact of apathy on memory functioning in patients with IPDWD. Background: Memory is one of the domains of neurocognitive functioning that…Psychometric Properties of the SCOPA-Cog Turkish version
Objective: The objective of this study is to adapt SCOPA-COG for Turkish-speaking patients with Parkinson's disease, ensuring it is both valid and reliable. This will…
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