Correlation of clinical profile of Parkinsonism with molecular imaging
Objective: CORRELATION OF CLINICAL PROFILE OF PARKINSONISM WITH MOLECULAR IMAGING (TRODAT AND PET-CT BRAIN) Background: The current study aims to establish the role of Molecular…Longitudinal imaging of regional volumes, presynaptic terminals and glucose metabolism in brains of people with early Huntington’s disease
Objective: To compare the sensitivity of 11C‑UCB‑J PET, 18F-FDG PET and volumetric MRI for detection of longitudinal brain changes in early Huntington’s Disease (HD). Background:…Clinical and functional determinants of motor reserve in patients with de novo Parkinson’s disease
Objective: To determine the clinical determinants and the role of serotonergic innervation on motor reserve in patients with de novo Parkinson's disease. Background: Patients with…The hypometabolism in anterior cingulate gyrus and thalamus: potential biomarkers of disease progression in progressive supranuclear palsy
Objective: This study aimed to identify differences in FDG uptake and metabolic covariant network (independent component analysis) in progressive supranuclear palsy (PSP) in comparison with…Substantia Nigra blood-brain barrier opening in Parkinson´s disease: PET (18F-Choline) evidence of parenchymal penetration
Objective: To evaluate clinical safety, feasibility, and tissue penetration (by 18F-Choline PET) of MR-guided focused ultrasound (MRgFUS) blood-brain barrier opening (BBB-O) of the substantia nigra…Clinical and radiological gender differences in Parkinson’s disease
Objective: To assess clinical and brain metabolic gender differences in a cohort of patients with PD Background: Many studies have elucidated gender-related clinical differences in…The impact of STN-DBS on brain metabolic activity during dynamic obstacle avoidance in Parkinson’s disease
Objective: To describe brain metabolic activity changes during dynamic obstacle avoidance in parkinsonian patients with subthalamic deep brain stimulation (STN-DBS) Background: STN-DBS does not offer…A network imaging biomarker of X-linked dystonia-parkinsonism
Objective: To characterize a metabolic brain network associated with X-linked dystonia-parkinsonism (XDP). Background: X-linked dystonia-parkinsonism (XDP, DYT/PARK-TAF1, Lubag) is an X-linked recessive movement disorder characterized…Non-tremor motor dysfunction in Parkinson’s disease is associated with decreased [18F]FMPEP-d2 binding
Objective: To explore the relationship between cannabinoid receptor type 1 (CB1) availability and motor symptoms in Parkinson’s disease (PD) with [18F]FMPEP-d2 positron emission tomography (PET).…An in-vivo study of regional synaptic density loss in patients with Multiple System Atrophy using [11C]UCB-J PET molecular imaging.
Objective: We present preliminary, cross-sectional data, on the in-vivo evaluation of pre-synaptic terminal density in the brain of patients with Multiple System Atrophy (MSA) compared…
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