Serum neurofilament light chain differentiates early Parkinson’s disease from progressive supranuclear palsy-parkinsonism
Objective: To assess the value of serum neurofilament light chain (NFL) levels in differentiating parkinsonian syndromes. Background: The diagnosis of Parkinson’s disease (PD) mostly relies…Cognitive Differences Between Men and Women with Progressive Supranuclear Palsy
Objective: (1) To evaluate the cognitive differences between men and women with progressive supranuclear palsy (PSP) and (2) to investigate whether sex has an effect…Inertial sensor-based kinematics in the differential diagnosis of Parkinson’s disease and atypical parkinsonisms
Objective: Assess the role of inertial sensors in the phenotyping and differential diagnosis of Parkinson’s Disease vs. Atypical Parkinsonisms Background: Wearable devices have been used…Midbrain/pons area ratio and clinical features predict the prognosis of Progressive Supranuclear Palsy
Objective: This retrospective study aims to characterize the natural history of PSP and to find predictors of shorter survival and faster decline of activity of…Correlations between amantadine usage, gait, and cognition in PSP: a post hoc analysis of the davunetide trial
Objective: Amantadine anecdotally improves gait and balance in PSP, potentially by increasing alertness, but there are no definitive data to support this observation. We investigated…The Impact of Progressive Supranuclear Palsy (PSP) Disease Severity on Caregivers
Objective: To quantify the impact of varying severity levels on caregivers’ burden and health-related quality of life (HRQoL). Background: PSP is a progressive disease. Patients…Ocular Motor Dysfunction as the Predictable Milestone of Life Prognosis in Progressive Supranuclear Palsy
Objective: The purpose of this study was to identify which symptoms predict the life prognosis in progressive supranuclear palsy (PSP). Background: Patients with PSP are…Aberrant structural connectivity of the executive network in Progressive Supranuclear Palsy
Objective: To ascertain the structural connectivity of the executive network in progressive supranuclear palsy (PSP) using probabilistic tractography. Background: Cognitive deficits are highly prevalent in…White matter abnormalities correlate with clinical features in PSP patients
Objective: To detect white matter abnormalities in PSP patients and their correlation with motor and cognitive impairment. Background: Progressive Supranuclear Palsy (PSP) is a tauopathy…Clinical Correlates of Genetic and Biomarker Profiles in Patients with Progressive Supranuclear Palsy: Data from the ARISE Study
Objective: To characterize the genetic and biomarker profile of patients with Progressive Supranuclear Palsy (PSP) and the relationship of potential biomarkers with baseline disease severity.…
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