The Impact of Progressive Supranuclear Palsy (PSP) Disease Severity on Caregivers
Objective: To quantify the impact of varying severity levels on caregivers’ burden and health-related quality of life (HRQoL). Background: PSP is a progressive disease. Patients…Ocular Motor Dysfunction as the Predictable Milestone of Life Prognosis in Progressive Supranuclear Palsy
Objective: The purpose of this study was to identify which symptoms predict the life prognosis in progressive supranuclear palsy (PSP). Background: Patients with PSP are…Aberrant structural connectivity of the executive network in Progressive Supranuclear Palsy
Objective: To ascertain the structural connectivity of the executive network in progressive supranuclear palsy (PSP) using probabilistic tractography. Background: Cognitive deficits are highly prevalent in…White matter abnormalities correlate with clinical features in PSP patients
Objective: To detect white matter abnormalities in PSP patients and their correlation with motor and cognitive impairment. Background: Progressive Supranuclear Palsy (PSP) is a tauopathy…Clinical Correlates of Genetic and Biomarker Profiles in Patients with Progressive Supranuclear Palsy: Data from the ARISE Study
Objective: To characterize the genetic and biomarker profile of patients with Progressive Supranuclear Palsy (PSP) and the relationship of potential biomarkers with baseline disease severity.…Baseline analysis of PROSPECT-M-UK: a longitudinal study of PSP, CBS and MSA
Objective: To complete the baseline analysis of clinical data from the PROSPECT-M-UK study and to assess the impact of applying current MDS PSP diagnostic criteria…Validation of the Movement Disorder Society criteria for the diagnosis of 4R-tauopathies
Objective: To validate the accuracy of the newly proposed Movement Disorder Society diagnostic criteria for progressive supranuclear palsy (MDS-PSP criteria, Höglinger et al., 2017) to…Molecular correlates of survival and clinical severity in Progressive Supranuclear Palsy
Objective: To test how regional tau pathology and neuroinflammation are associated with clinical severity and survival in progressive supranuclear palsy (PSP). Background: The abnormal aggregation…Validation of the diagnostic criteria for progressive supranuclear palsy in pathologically confirmed patients
Objective: To assess the sensitivity and specificity of the diagnostic criteria for progressive supranuclear palsy (PSP). Background: The International Parkinson and Movement Disorder Society criteria…Concomitant brain pathologies have no major impact on clinical milestones in progressive supranuclear palsy
Objective: To analyze the frequency and severity of co-pathologies in PSP patients and their relevance for the clinical presentation and progression in PSP. Background: The phenotypic…
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