Clinical progression of PSP-Richardson’s syndrome and other PSP variants in an East Asian cohort
Objective: This study aimed to compare longitudinal clinical progression between patients with progressive supranuclear palsy–Richardson syndrome (PSP-RS) and those with PSP-subcortical phenotypes. Background: PSP is…Predictors of disease progression in progressive supranuclear palsy and corticobasal syndrome
Objective: To identify predictors of survival and progression in progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS). Background: Reported median survival in PSP and CBD…Sleep symptoms in people with Progressive Supranuclear Palsy in Argentina
Objective: To report sleep features and symptoms in a longitudinal prospective cohort of people with PSP from Argentina (CAITauP cohort). Background: Progressive supranuclear palsy (PSP),…Cholinergic Systems Changes Associated with Freezing of Gait in Progressive Supranuclear Palsy
Objective: To investigate whether distinctive cholinergic system changes are associated with FoG in PSP patients. Background: Freezing of gait (FoG) is a profound mobility disturbance…Clinical and Cognitive Profile in Patients with Atypical Parkinsonian Syndromes: A Longitudinal Study from a Tertiary Care Center
Objective: To characterize the clinical profile, cognitive performance, sleep and psychiatric features among patients with atypical parkinsonism. Background: Atypical Parkinson syndromes (APS) are group of…Microstructural cortical alterations are related to cognitive and disease severity in progressive supranuclear palsy
Objective: To study cortical microstructural alterations in patients with progressive supranuclear palsy (PwPSP) and their associations with both cognitive and clinical symptoms. Background: Midbrain’s atrophy on structural…Phenotypic and Genotypic Spectrum of MAPT-associated Parkinsonism in a Multi-ethnic Malaysian Cohort
Objective: To describe the phenotypic continuum and genotypic spectrum of microtubule-associated protein tau (MAPT)-associated parkinsonism in a multi-ethnic Malaysian cohort. Background: Carriers of pathogenic MAPT…Determinants of Re-diagnosis of Parkinson’s Disease to Atypical Parkinsonism: Results from the Tracking Parkinson’s Cohort (PRoBAND) and Oxford Parkinson’s Discovery Cohort (OPDC) Cohorts
Objective: We aim to identify the clinical and biomarker features which best predict re-diagnosis to a Parkinson plus syndrome (PPS) in those initially diagnosed with…Sex Differences in Vascular Burden, Neurodegeneration, and Clinical Progression in Progressive Supranuclear Palsy Richardson Syndrome
Objective: To examine sex differences in cardiovascular risk, white matter hyperintensities (WMH), and neurodegeneration, and to determine their relationship with clinical progression in progressive supranuclear…Insights on the Groaning Phenomenon from a Large Asian Progressive Supranuclear Palsy Cohort
Objective: We investigated the frequency and phenomenology of groaning in progressive supranuclear palsy (PSP), and its association with disease parameters and caregiver burden. Background: “Purposeless”…
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