Hierarchical Machine Learning Classification of Parkinsonian Disorders using Saccades
Objective: To evaluate the discriminative power of a novel saccade waveform reconstruction approach compared to conventional saccadic metrics in differentiating Parkinson's disease (PD), progressive supranuclear…Dermal 4R-Tau seeding as a novel biomarker for Progressive Supranuclear Palsy
Objective: To ascertain the presence of misfolded tau species in the skin of Progressive Supranuclear Palsy (PSP) patients and evaluate its utility as a potential…The links between frontal deficits and levels of inflammatory parameters in Progressive Supranuclear Palsy
Objective: The goal of the research was to verify the possible association between the levels of inflammatory factors and frontal deficits in Progressive Supranuclear Palsy…Validation of Inertial Monitoring Units for Gait Assessment in Progressive Supranuclear Palsy
Objective: To evaluate the validity and precision of using inertial measurement units (IMU) for measurement of kinematics and spatial-temporal features of gait in progressive supranuclear…Linear Mixed-Effect Modelling of Antisaccades in Parkinson’s Disease and Progressive Supranuclear Palsy
Objective: This study aims to investigate variations in antisaccade parameters (latency, damping ratio, peak velocity, and amplitude) among different stages of Parkinson's Disease (PD), Progressive…Legmain/Asparaginyl endopeptidase-resistant tau fibril fold produces corticobasal degeneration-specific C-terminal tau fragment
Objective: This study monitored the formation of CBD (corticobasal degeneration)-type fibrils that exhibit astrocytic plaques, a characteristic CBD pathology, using Legumain-cleavage site-specific antibodies and CBD-specific…Peripheral inflammation severity in differential diagnosis of progressive supranuclear palsy and multiple system atrophy – usefulness of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and neutrophil-to-high-density lipoprotein-cholesterol ratio
Objective: Assessment of the possible differences in peripheral inflammation severity between progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) with the use of three…Ethnic Diversity and Symptomatology in Parkinson’s Disease with a Focus on Falls and Vertical Gaze Palsy
Objective: The objective of this study was to explore atypical features in the clinical phenotype of people with Parkinson’s disease (PwP) enrolled in the East…Can Square Wave Jerks Differentiate Progressive Supranuclear Palsy from Parkinson’s Disease? A Scoping Review
Objective: To review the available literature regarding the presence and properties of square wave jerks (SWJs) in Progressive Supranuclear Palsy (PSP) and Parkinson’s Disease (PD).…Inclusion of PSP-Parkinsonism (PSP-P) phenotype in clinical trials – power calculation
Objective: PSP-P is the second most common PSP phenotype. To facilitate its inclusion in future clinical trials, we used longitudinal data from the TAUROS study…
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