Tracking RBD and PD progression with longitudinal structural brain connectomes
Objective: To compare longitudinal structural connectomes derived from whole brain dMRI and PD clinical rating scales as a disease progression biomarker, on three cohorts: de-novo…Free-living gait in REM sleep behaviour disorder: Measures of prodromal Parkinson’s disease?
Objective: The aim of this study was to investigate if free-living gait monitoring can discriminate individuals with REM sleep behaviour disorder (RBD) from controls. Background:…Polysomnographic data in Dementia with Lewy Bodies: Correlation with clinical features and comparison with other alfa-synucleinopathies
Objective: 1) Polysomnography (PSG) assessment of sleep in Dementia with Lewy Bodies (DLB). 2) Correlation between PSG data, fluctuations and hypersomnolence. 3) Comparison of PSG…Comparisons of cerebral glucose metabolism and striatal DAT binding in PD patients with and without RBD
Objective: This study aims to identify the differences of functional neuroimaging phenotype between Parkinson’s disease (PD) patients with REM sleep behavior disorder (RBD) (PD+RBD+) and…Preliminary evidence for an altered relationship between uric acid levels and resting state functional connectivity in REM sleep behavior disorder
Objective: To determine the relationship between uric acid (UA) levels and functional connectivity in REM sleep behavior disorder (RBD) compared to controls. Background: UA levels…Diminished fMRI global signal differences between eyes closed and eyes open resting state in RBD and PD
Objective: test whether patients with Parkinson’s diseases (PD) and REM sleep behavior disorder (RBD) exhibit diminished state-related changes in their resting state fMRI global signal.…Exploring the neural correlates of gait asymmetry in idiopathic REM Sleep Behaviour Disorder
Objective: Given the typical asymmetric onset of motor symptoms in PD, the current study sought to investigate whether patients with iRBD show evidence of asymmetric…In vivo staging of pathology in REM sleep behaviour disorder
Objective: To study the level of dysfunction in the peripheral and central nervous system in idiopathic REM sleep behaviour disorder (iRBD) patients. Background: α-synuclein (α-syn)…Efficacy of prolonged release melatonin for REM sleep behaviour disorder in Parkinson’s disease: A double blind, randomised, placebo-controlled trial
Objective: Test the efficacy of prolonged-released melatonin for REM sleep behaviour disorder (RBD) in Parkinson’s disease (PD). Background: Half of all PD patients experience RBD…Temporal evolution of biomarkers from healthy ageing, isolated REM sleep behavior to early Parkinson’s disease
Objective: To study the temporal evolution of biomarkers of various modalities in healthy ageing controls (HC), the prodromal condition of isolated REM sleep behavior disorder…
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