Evaluation of Neuroprotective Effect of Terminalia macroptera on Rotenone Induced Parkinson’s Disease in Mice
Objective: This study investigates the neuroprotective effects of an aqueous extract of Terminalia macroptera (AETM) in a rotenone-induced Parkinsonism mouse model. Background: Parkinson’s disease (PD)…Carvacrol modulates rotenone-induced Nigrostriatal Neuronal Death and Angiogenesis via targeting AMPK/FOXO3 transcription factor O3 Signaling cascade
Objective: With an eye toward its effects on striatal angiogenesis and the AMPK/ FOXO3 transcription factor O3 pathway, this work attempts to investigate the neuroprotective…Phosphorylated High Mobility Group Box Protein 2 (HMGB2) as a Potential Biomarker for Parkinson’s Disease
Objective: We recently showed that HMGB2 is secreted during ferroptosis and as ferroptosis is involved in the etiology of PD, we have examined the possibility…Vitamin D3 Supplementation Ameliorates Non-Motor Symptoms Associated with Parkinson’s Diseases in a Rotenone Model in Wistar Rats
Objective: This study investigated the role of VD3 supplementation on non-motor symptoms and its mechanism of action in a rotenone rat model of PD. Background:…The Protective Effect of Sutherlandia frutescens in a Rotenone-Induced Rat Model of Parkinson’s Disease.
Objective: The objective of this study was to investigate the impact of rotenone, a pesticide associated with Parkinson's-like symptoms, and Sutherlandia frutescens (SF), a plant…Manganese-induced Parkinsonism Vs Rotenone-induced Parkinsonism: Animal Life Matters!
Objective: To evaluate the Parkinsonism mimicking potential of MnCl2 in an experimental rat model.To compare the destructive effect of MnCl2 with rotenone by performing behavioral,…Systematic Review and Meta-Analysis of Pesticide Exposure and the Risk of Parkinson’s Disease
Objective: This study aimed to investigate the association between exposure to pesticides and the risk of Parkinson’s disease (PD). Background: PD is the second most…Neuroprotective Effect of Isoquercitrin in Rotenone Induced Parkinson’s Disease-Like Motor and non-motor Symptoms in Zebrafish
Objective: The objective of study is to find out the effect of isoquercitrin, a plant-derived chemical, against Parkinson-like symptoms induced by rotenone in zebrafish.. Background:…Preclinical Studies: Investigating Serum-Based Exosomal miRNAs in Prodromal Drug-Induced Parkinson’s Disease
Objective: This work aims to elucidate the identification of homologs of miRNAs in a pronormal stage of Parkinson`s disease. Background: Parkinson's disease (PD) is defined…Deciphering the Role of Auranofin-Loaded Nanoparticles Against Rotenone Model of Parkinson’s Disease: Via GSK-3β/ Nrf2/HO-1 Signaling Pathways
Objective: To investigate the neuroprotective effect of AUF-loaded nanoparticles in animal models of Parkinson's disease by modulating GSK-3β/ Nrf2/HO-1 Signaling Pathways. Background: Parkinson's disease (PD) is…
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