Association between sleep disturbances in Parkinson’s disease and bioimaging
Objective: We investigated whether bioimaging for Parkinson’s disease (PD) such as metaiodobenzylguanidine (MIBG) myocardial scintigraphy and 123I-ioflupane SPECT (DaTSPECT) are useful for biomarker of sleep…Automated Interpretation of FP-CIT-SPECT images based on Artificial Intelligence
Objective: Our objective is to develop an AI-based approach to automatically rate FIP-CIT-SPECT data. Background: FP-CIT-SPECT visualizes the integrity of nigro-striatal dopaminergic synapses in vivo.…Relations of clinical symptoms with dopamine transporter imaging in untreated Parkinson’s disease
Objective: The aim of the present study was to determine the relations of clinical symptoms with nigrostriatal neuron loss in untreated patients with Parkinson's disease…Effect of polygenic load on striatal dopaminergic deterioration in Parkinson’s disease
Objective: To investigate the longitudinal association between PD-associated polygenic load and the striatal dopaminergic activity using 123I-N-3-fluoropropyl-2-beta-carboxymethoxy-3beta-(4-iodophenyl) nortropane (123I-FP-CIT) single photon emission computed tomography (SPECT).…Age-related failure in compensatory mechanisms and its relation to the Parkinson phenotype: evidence from a SPECT study in early and late-onset PD
Objective: To investigate if a less prominent dopaminergic dysfunction on 123I-ioflupane SPECT imaging (DaTSCAN) despite a more severe motor phenotype in Late Onset Parkinson’s Disease…Correlation between Pareidolia and cerebral perfusion by SPECT in Parkinson’s disease without dementia: A retrospective study
Objective: The aim of this study is to investigate the correlation between the number of illusory responses on the Pareidolia test and cerebral perfusion in…Extrastriatal dopaminergic and serotonergic pathways in Parkinson’s disease and in dementia with Lewy bodies: a 123I-FP-CIT study
Objective: To evaluate the common and divergent dopaminergic and serotonergic impairment in Parkinson's disease and dementia with Lewy bodies using 123I-FP-CIT imaging. Background: Striatal dopaminergic…Striatal dopaminergic regulation of micrographia in parkinsonism
Objective: To investigate the role of brain dopamine function in writing and drawing micrographia of patients with parkinsonism. Background: Micrographia, an abnormally small or progressively…Clinical, genetic and radiological characterization of patients with movement disorders and basal ganglia calcification
Objective: The aim of this study is to present a case series of patients affected by movement disorders and Fahr’s disease or Primary Familial Brain…123I-FP-CIT SPECT imaging in early PD patients versus mid and late onset PD: Longitudinal data from the PPMI study
Objective: To determine whether there are longitudinal differences in dopaminergic denervation [as exemplified by signal reduction in 123I-FP-CIT SPECT] in early PD patients versus mid…
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