Inertial-sensor based full-body kinematics reveals an unstable gait with increased variability in patients with evidence of dopaminergic denervation with 123I-FP-CIT SPECT
Objective: Distinguish patients with and without dopaminergic denervation (as assessed by 123I-FP-CIT-SPECT – DaTscan) with Inertial-sensor full body kinematics (FBK) assessment. Background: The differential diagnosis…Nigrostriatal degeneration in DYT-PRKRA: new insights on a rare disorder
Objective: To describe a genetically proven DYT-PRKRA (DYT16) case with documented loss of presynaptic dopamine transporters. Background: DYT-PRKRA is an autosomal recessive disorder combining generalized…Asymmetrical striatal dopamine transporter binding correlates with excess contralateral rest tremor
Objective: To investigate the relationship between striatal dopamine transporter binding and rest tremor. Background: In vivo dopamine transporter imaging is a useful tool for distinguishing…Executive functions correlate with DaT-SPECT laterality in Parkinson’s disease
Objective: The aim of this study is to assess whether the impairment of executive functions is associated with the laterality of the affected nigro-striatal pathway…Motor compensation in Parkinson’s disease: a multimodal neuroimaging study
Objective: To study motor compensation mechanisms in Parkinson's disease. Background: Whereas akinesia in Parkinson's disease (PD) is linked to dopaminergic neurons death and striatal dopamine depletion,…No link between striatal dopaminergic axons and dopamine transporter imaging in Parkinson’s disease
Objective: The objective of this study was to investigate if dopamine transporter (DAT) binding is associated with dopaminergic neurites in the putamen. Background: Dopamine transporter…Association between sleep disturbances in Parkinson’s disease and bioimaging
Objective: We investigated whether bioimaging for Parkinson’s disease (PD) such as metaiodobenzylguanidine (MIBG) myocardial scintigraphy and 123I-ioflupane SPECT (DaTSPECT) are useful for biomarker of sleep…Automated Interpretation of FP-CIT-SPECT images based on Artificial Intelligence
Objective: Our objective is to develop an AI-based approach to automatically rate FIP-CIT-SPECT data. Background: FP-CIT-SPECT visualizes the integrity of nigro-striatal dopaminergic synapses in vivo.…Relations of clinical symptoms with dopamine transporter imaging in untreated Parkinson’s disease
Objective: The aim of the present study was to determine the relations of clinical symptoms with nigrostriatal neuron loss in untreated patients with Parkinson's disease…Effect of polygenic load on striatal dopaminergic deterioration in Parkinson’s disease
Objective: To investigate the longitudinal association between PD-associated polygenic load and the striatal dopaminergic activity using 123I-N-3-fluoropropyl-2-beta-carboxymethoxy-3beta-(4-iodophenyl) nortropane (123I-FP-CIT) single photon emission computed tomography (SPECT).…
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