Circadian cycle and disease phenotype in Parkinson’s disease, insights by motion sensors and molecular biology.
Objective: Our aim is to investigate whether the circadian cycle (CC) is linked to the patient Parkinson's disease (PD) profile on a clinical and molecular…POOR SLEEP QUALITY AND OBESITY IN PATIENTS WITH PARKINSON’S: PRELIMINARY RESULTS OF A COHORT STUDY
Objective: Describe the prevalence of overweight and obesity in patients with PD who have poor quality sleep. Background: Sleep disturbances are common and often severe…Automated scoring of REM sleep without atonia using the open-source software RBDtector
Objective: To facilitate quantification of REM sleep without atonia (RSWA) and thereby identify patients with rapid eye movement (REM) sleep behaviour disorder (RBD). Background: RBD…Validation of a wireless Home-Based Sleep Laboratory for assessment of sleep-related disorders in Parkinson’s disease
Objective: To examine the validity of a new wireless wearable system which measures EEG, EOG and sEMG for the assessment of sleep and sleep related…Alpha-synuclein fibril-based mouse model of REM sleep behavior disorder as a prodrome of synucleinopathy
Objective: To investigate whether in wild-type mice, inoculation of α-synuclein (aSyn) preformed fibrils (PFFs) into the sublaterodorsal tegmental nucleus (SLD), a core structure associated with…Utilising multiple murine models to investigate sleep and circadian system dysfunction in PD
Objective: We aimed to investigate the impact of alpha-synuclein aggregation and spreading, and nigrostriatal dopaminergic degeneration on sleep homeostasis and circadian function. Background: Sleep dysfunction…Slow wave activity as a marker of levodopa induced dyskinesia
Objective: To assess the role of slow wave activity during slow wave sleep (SWS-SWA) as a marker of levodopa induced dyskinesia (LID) development in Parkinson's…Impact of Chronotypes and melatonin levels on sleep disorders in patients with Parkinson’s disease
Objective: To investigate the sleep problems and circadian rhythm abnormalities in PD patients using sleep evaluation scale – Parkinsons disease sleep scale (PDSS) for mild…REM density in isolated REM sleep without atonia
Objective: To investigate REM density in patients with isolated REM sleep without atonia. Background: Isolated RSWA (iRSWA) is regarded as a prodromal phase of REM…Augmented Brain Wave Synchronicity in Sleep in Parkinson’s Disease Patients
Objective: Sleep dysfunction in Parkinson’s disease (PD) is a commonly reported symptom. Background: Analysis of brain wave synchronicity may help to unravel this phenomenon and…
