Modulation of microglia function in the prion-like spreading of α-synuclein in the murine brain
Objective: We aimed to analyze the influence of two microglia-related pathways on the accumulation of α-synuclein aggregates and neurodegeneration after intracerebral injection of sonicated murine…Piperine potentiates neuroprotective effect of curcumin in MPTP model of Parkinson’s disease in rats: Impact on neurochemical modulation
Objective: (1) Curcumin is well tolerated phenolic compound used for CNS disorder but problem is its low oral bioavailability and (2) Piperine is combined to…Finding an optimal lead trajectory for a better stimulated volume in movement disorder therapy
Objective: Defining the best lead trajectory (Arc; Ring) with a computational 3D stereotactic model of the Globus Pallidus internus (GPi) and investigating the influence of…Reflex saccades changes can estimate long-term symptom progression in DBS STN and MED Parkinson’s disease patients (PD)
Objective: The aim of this study was to evaluate the impact of STN DBS on RS parameters in PD. We have compared disease progression in…The impact of STN DBS on kinetic tremor in Parkinson’s disease patients
Objective: The aim of the study is to evaluate the impact of STN DBS on kinetic tremor in PD patients in comparison to pharmacologically treated…Stimulation of the globus pallidus internus in the treatment of Parkinson’s disease: Long-term results of a monocentric follow-up
Objective: To investigate the long-term outcome of pallidal deep brain stimulation (GPi-DBS) in Parkinson's disease (PD). Background: GPi-DBS is beneficial in patients with advanced levodopa-responsive…Stereotactic pallidotomy for Parkinson’s disease in El Salvador: One year follow up
Objective: Characterize patients with idiopathic Parkinson's disease undergoing posteroventral pallidotomy. Assess improvement in motor symptoms after pallidotomy. Background: Parkinson's disease is a neurodegenerative disease with…Quantification of tremor and rigidity during deep brain stimulation surgery for Parkison’s disease
Objective: The aim of this study is to validate practical and objective measures to assess changes in rigidity and tremor due to micro-lesion effects and…A multi-site survey of Parkinson’s disease deep brain stimulation center best practice: moving toward a standard of care for DBS
Objective: To survey how Deep Brain Stimulation (DBS) Centers handle referrals and peri-operative (surgical and non-surgical) treatment of persons with Parkinson's disease (PD). Background: Currently…MR-guided high intensity focused ultrasound in Parkinson’s disease: A series of 5 cases
Objective: We present results of an ongoing trial of unilateral transcranial MR-guided high intensity focused ultrasound (tcMRgFUS) ablation of the pallido-thalamic tract (PTT, fasciculus thalamicus)…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.