Mapping aggregate monopolar sensing data of beta power local field potentials onto a common subthalamic nucleus in Parkinson’s disease patients
Objective: Compare local field potential (LFP) magnitude and anatomical location measured from a chronically implanted deep brain stimulation (DBS) lead within the subthalamic nucleus (STN)…Broad spectrum local field potential activities as a novel biomarker for adaptive deep brain stimulation
Objective: This study aims to evaluate the wider frequency range (1-200 Hz) LFPs as the novel neural biomarkers for adaptive DBS. In parkinsonism rats, we…Characterization of DBS-induced Speech Improvements in a German PD Cohort
Objective: To investigate speech changes induced by subthalamic deep brain stimulation (DBS) in persons with Parkinson’s disease (pwPD). Background: Dysarthria is a common debilitating motor…Approaches to understanding the role of STN in the development of ICD in Parkinson’s disease
Objective: The aim of this study was to identify the features of subthalamic tracts in PD patients with ICD. Background: Recurrent negative feedback loops from…Subthalamic versus Pallidal Temporal Interference Stimulation in Parkinson’s Disease: A Pilot Study
Objective: To investigate whether transcranial temporal interference stimulation (tTIS) targeting different deep brain regions produces symptom-specific improvements consistent with established deep brain stimulation (DBS) outcomes…Bayesian Re-Analysis of Phase I and II Subthalamic Nucleus Perfusion Changes Following Mesenchymal Stem Cell Infusion in Parkinson’s Disease
Objective: To compare subthalamic nucleus (STN) perfusion changes following mesenchymal stem cell (MSC) infusion in Parkinson’s disease (PD) using Bayesian methods in both Phase I…Impact of Patient-Specific Structural Connectivity of STN-DBS on Balance and Mobility – Pilot study
Objective: To evaluate the impact of patient-specific structural connectivity between VTA in STN targeting and SMA/preSMA on functional mobility improvements in PD patients undergoing DBS.…Predictors of Cognitive Impairments and Mood Disorders after Subthalamic Deep Brain Stimulation in Patients with Parkinson’s Disease
Objective: We aimed to determine the predictors of cognitive decline and mood disorders after STN-DBS in PD. Background: Cognitive impairment and mood disorders are the…Subthalamic Nucleus Stimulation May Suppress Both Ipsilateral and Contralateral Local-Field-Potential Magnitude
Objective: Determine whether ipsilateral subthalamic nucleus (STN) stimulation affects local field potential (LFP) power in the contralateral STN to inform clinical decision making. Background: A…Traditional Deep Brain Stimulation Programming versus Automated Image-Guided Algorithm in Patients with Parkinson’s Disease
Objective: To compare traditional initial deep brain stimulation (DBS) programming with artificial intelligence (AI)-assisted automated image-guided DBS programming algorithm. Background: DBS programming is a complex,…
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