Prediction of Cognitive Decline After STN-DBS in Parkinson’s Disease Using Preoperative Electroencephalography and a Deep Learning Model
Objective: To determine whether preoperative electroencephalography (EEG) combined with deep learning can predict cognitive decline 1 year after subthalamic deep brain stimulation (STN-DBS) in patients…Automatic Segmentation of the Subthalamic Nucleus and Globus Pallidus Internus: Can it support planning and programming in Deep brain stimulation
Objective: Whether auto-segmentation matches anatomy?Whether auto-segmentation volume difference in either side matches UPDRS score difference between two sides?whether auto-segmentation volume depends on MRI sequence?Whether auto-segmentation…Subthalamic Nucleus Deep Brain Stimulation Modulates Cortical Activation During Kinesthetic Illusion in Parkinson’s Disease: An fMRI Study
Objective: To investigate how subthalamic nucleus deep brain stimulation (STN-DBS) modulates cortical activation during kinesthetic illusion (KI) in Parkinson’s disease (PD). Background: There is increasing…In Silico Investigation of Dopamine Receptor–Calcium Channel Coupling in Subthalamic Nucleus Neurons: Implications for Parkinson’s Disease Therapy
Objective: Parkinson’s disease (PD) is characterized by disrupted dopaminergic signaling within the basal ganglia circuitry, particularly affecting the activity of subthalamic nucleus (STN) neurons [1,…Probabilistic Mapping of Subthalamic Beta and Theta Subcircuits Reveals Segregated Connectivity and Deep Brain Stimulation Outcomes in Parkinson’s Disease
Objective: To map theta- and beta-band activity within the subthalamic nucleus (STN) and examine associations with motor improvement and impulsive behavior in Parkinson’s disease (PD)…Oscillatory characterization of the STN beyond the resting state in patients with Parkinson’s disease.
Objective: To explore how STN oscillatory activity varies in patients with PD implanted with DBS during motor states that are closer to everyday life yet…Therapeutic Efficacy of a Next-Generation 16-Contact Directional Deep Brain Stimulation System in Parkinson’s Disease
Objective: We assessed the clinical efficacy and safety of a novel deep brain stimulation (DBS) system equipped with 16-contact directional leads in improving motor symptoms…Ion Channel Modulation by Dopamine Receptors in Subthalamic Nucleus Neurons: Implications for Parkinson’s Disease Pathophysiology
Objective: Recent neurophysiological studies indicate that dopamine D2 receptors (D2R) may interact with N-type calcium channels in neurons of the subthalamic nucleus (STN), potentially altering…Three-Year Results from the Largest Prospective Cohort of Directional Subthalamic Deep Brain Stimulation in Parkinson’s Disease to Date
Objective: To evaluate long-term real-world motor, quality-of-life, medication, and safety outcomes in patients with Parkinson’s disease (PD) treated with a multiple-independent-current-control (MICC) directional deep brain…Electrode localization in STN deep brain stimulation using image reconstruction from an emerging DBS program in the Dominican Republic
Objective: To describe DBS electrode localization using Lead-DBS reconstruction and explore its relationship with motor improvement measured by MDS-UPDRS III. Background: Deep brain stimulation of…
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