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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Tauopathies"

  • 2024 International Congress

    Dermal 4R-Tau seeding as a novel biomarker for Progressive Supranuclear Palsy

    I. Martinez-Valbuena, D. Olszewska, M. Sousa, T. Abkur, N. Bendahan, N. Reyes, M. Emamikhah Abarghouei, C. Ghadery, L. Armengou Garcia, J. Liao, C. Tan, SM. Fereshtehnejad, H. Alotibi, JC. Vargas-Gonzalez, NC. Dimal, J. Li, P. Bhakta, R. Cheung, J. Sasitharan, N. Visanji, S. Fox, C. Tartaglia, A. Lang, G. Kovacs (Toronto, Canada)

    Objective: To ascertain the presence of misfolded tau species in the skin of Progressive Supranuclear Palsy (PSP) patients and evaluate its utility as a potential…
  • 2024 International Congress

    Is cathepsin D a good target for therapy in Tau-related conditions?

    G. Kovacs, A. Jafrani, G. Puska, I. Martinez-Valbuena, S. Lee, S. Knott, A. Karakani, S. Tanikawa, A. Lang, S. Forrest (Toronto, Canada)

    Objective: To study the involvement of cathepsin D in the pathogenesis of Tau-related conditions. Background: The endo-lysosomal system (ELS) is central in processing of neurodegenerative…
  • 2024 International Congress

    Tau Deposition in Locus Coeruleus is Associated with Rapid Eye Movement Sleep Behavior Disorder in Progressive Supranuclear Palsy.

    X. Li, FT. Liu (Shanghai, China)

    Objective: In this study, we aimed to investigate the frequency of Rapid eye movement sleep behavior disorder (RBD) occurring in a large cohort of PSP,…
  • 2024 International Congress

    Longitudinal progress and clinical relevance of 18F-Florzolutau PET in patients with PSP: a one-year follow-up study

    J. Wang, F. Liu, C. Zuo (Shanghai, China)

    Objective: Here we aimed to explore the progress of 18F-Florzolotau PET and its clinical relevance in patients with PSP during one-year follow-up. Background: The 18F-Florzolotau…
  • 2024 International Congress

    Clinical and neuroimaging factors associated with survival in Progressive Supranuclear Palsy

    G. Martí-Andrés, E. Prieto-Azcarate, CA. Espinoza-Vinces, L. van Bommel, S. Meles, M. Riverol, KL. Leenders, J. Arbizu, MR. Luquin-Puido (Pamplona, Spain)

    Objective: To assess clinical and neuroimaging factors associated with survival in a cohort of patients with a final clinical diagnosis of Progressive Supranuclear Palsy (PSP)…
  • 2024 International Congress

    Development and Validation of a Clinical Scale for Distinguishing Multiple System Atrophy from 4-Repeat Tauopathies

    I. Ruiz Barrio, A. Horta Barba, A. Puig Davi, I. Aracil Bolaños, A. Quattrone, S. Martinez Horta, J. Kulisevksy, J. Pagonabarraga (Barcelona, Spain)

    Objective: We aimed to develop a clinical scale that distinguishes between Multiple System Atrophy (MSA) and 4-repeat tauopathies (4RT: CBD, PSP) using a standardized neurological…
  • 2024 International Congress

    Environmental risk factors and demographic of patients with Progressive Supranuclear Palsy from Argentina

    F. Rellan, B. Couto, F. Gonzalez Del-Boca, M. Paez Magio, C. Villa, E. Franchello, G. Alvarado, G. Mizraji, D. Nadile, C. Tanner, O. Gershanik, C. Marras (Buenos Aires, Argentina)

    Objective: To describe the environmental risk factors and family history in Argentinian patients with diagnosis of progressive supranuclear palsy (PSP). Background: Background: The current epidemiology…
  • 2024 International Congress

    18F-Florzolotau Positron Emission Tomography Imaging Correlates with Regional Brain Atrophy and Plasma Biomarkers in Tauopathy Parkinsonism Syndrome

    CH. Li, SP. Fan, MC. Shih, YH. Weng, TF. Chen, IT. Hsiao, KJ. Lin, CH. Lin (Hsinchu, Taiwan)

    Objective: We aim to investigate the relationship between regional 18F-florzolotau uptake and clinical severity, structural volume changes, and plasma markers in tauopathy parkinsonism syndrome. Background:…
  • 2024 International Congress

    Cytokine Profiles as Biomarkers for Neurodegenerative Diseases: An inflammatory study on Parkinson’s Disease and Tauopathies

    A. Jäck, W. Wilfert, C. Palleis, A. Bernhardt, E. Weidinger, S. Katzdobler, U. Fietzek, D. Teupser, J. Levin (Munich, Germany)

    Objective: To investigate the diagnostic and prognostic value of cytokine profiles in cerebrospinal fluid (CSF) and serum of patients with Parkinson's Disease (PD), Progressive Supranuclear…
  • 2024 International Congress

    18F-Florzolotau PET uncovers the Co-pathological Heterogeneity of Tau Protein in Dementia with Lewy Bodies

    G. Tang, XY. Li, FT. Liu, J. Wang (Shanghai, China)

    Objective: We attempted to reveal the topographical deposition patterns of tau proteins in the living brains of patients with DLB in vivo by virtue of…
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