Impaired intracortical inhibition predicts response to medication in Parkinson’s disease patients
Objective: To check whether measures of motor cortex excitability and plasticity are associated with clinical response to dopaminergic treatment in Parkinson’s disease (PD) patients. Background:…Effect of rTMS over supplementary motor area on motor cortical excitability: a study using realistic sham stimulation as placebo
Objective: To clarify the neurophysiological after-effect of repetitive transcranial magnetic stimulation (rTMS) over supplementary motor area (SMA) which had been shown to improve motor symptoms…Continuous levodopa- carbidopa gel recovers motor cortex plasticity in advanced Parkinson’s disease
Objective: The objective of this study was to investigate if continuous infusion of levodopa- carbidopa gel (LCIG) improves motor complications of Parkinson's disease (PD) and…Central cholinergic activity and risk of falls in patients with Parkinson’s disease and freezing of gait
Objective: We evaluated whether changes in cholinergic function might be related to increased fall risk in PD patients with Freezing of Gait (FoG). Background: FoG…Randomized controlled trial of 1Hz SMA rTMS + gait training for Freezing of Gait
Objective: To determine the effects of 1Hz supplementary motor area (SMA) repetitive transcranial magnetic stimulation (rTMS) and gait training on freezing of gait (FOG). Background:…Examining supplementary motor area-primary motor cortex connectivity in tremor-dominant Parkinson’s disease using a novel transcranial magnetic stimulation protocol to inform clinical practice
Objective: Objectives: (1) Measure test re-test reliability of dual-coil transcranial magnetic stimulation (TMS) measures of supplementary motor area-primary motor cortex connectivity (SMA-M1 connectivity). (2) Investigate…Meta-Analysis of Short-afferent inhibition and Cognitive Impairment in Parkinson’s Disease
Objective: In this meta-analysis, we assess whether short-afferent inhibition (SAI) is impaired in Parkinson's disease (PD) patients as well as identify clinical variables associated to…Further insights into excitatory-inhibitory balance of the primary motor cortex in Parkinson’s disease: A triple-pulse stimulation study
Objective: To characterize intracortical facilitation and inhibition of the primary motor cortex (M1) in Parkinson’s disease (PD) using transcranial magnetic stimulation (TMS). Background: Since introduction…Motor cortical inhibitory and facilitatory circuit interactions in Parkinson’s disease
Objective: To determine how intracortical circuits interact with one another in Parkinson’s disease. Background: Using transcranial magnetic stimulation (TMS), previous work has established that motor…Anti-glutamatergic effect of safinamide in Parkinson’s Disease: A TMS study
Objective: To test the effect of safinamide, at the doses of 50 and 100 mg/day, on primary motor cortex (M1) excitability and glutamatergic neurotransmission in…
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