A phase 2b, randomized, dose-response study of SAGE-324/BIIB124 for the treatment of essential tremor: KINETIC 2 trial in progress
Objective: The phase 2b KINETIC 2 trial is a double-blind, randomized, placebo-controlled, dose-response study designed to evaluate SAGE-324/BIIB124 (SAGE-324) for the treatment of patients with…Preclinical Characterization of Suvecaltamide for Essential Tremor
Objective: To characterize the in vitro T-type calcium (CaV3) channel target pharmacology and in vivo anti-tremor profile of suvecaltamide (JZP385, CX-8998). Background: CaV3 channels, a…Clinical effectiveness and economic impact of transcutaneous afferent patterned stimulation therapy for essential tremor in a real-world setting: protocol for a pragmatic trial
Objective: To determine the feasibility of delivery, clinical effectiveness, healthcare resource utilization (HCRU) and costs of transcutaneous afferent patterned stimulation (TAPS) therapy for the treatment…Intraoperative quantification of MDS-UPDRS tremor measurements using 3D accelerometry
Objective: This study focuses on translating parkinsonian tremor tests to an objective method to rate tremor severity using 3D accelerometry, that can be used during…Treatment of upper limb dystonic tremors: a retrospective study
Objective: Our study aimed to evaluate the clinical outcome of patients with upper-limb dystonic tremor (UL-DTs) treated at a tertiary hospital in London. Background: Tremor…Transcranial static magnetic field stimulation of the primary motor cortex in essential tremor
Objective: To test the acute therapeutic effects of transcranial static magnetic field stimulation (tSMS) of the primary motor cortex in patients with essential tremor. Background:…Characterization of essential tremor patients in a central hospital-based sample.
Objective: Determine characteristics of essential tremor (ET) patients in a hospital-based sample. Background: Essential tremor is the most frequent movement disorders, with an estimated prevalence…Dual target deep brain stimulation for clinically complex tremor disorders: a single centre prospective study
Objective: We present a case series of patients with refractory complex tremor treated with dual targeting DBS of ViM and pSTN/cZI. Background: The ventral intermediate (ViM) nucleus…Electrical stimulation of muscle afferents for tremor reduction in essential tremor patients
Objective: To describe the preliminary clinical results of a research project on electrical stimulation of muscle afferents to reduce tremor in patients with Essential Tremor…Effect of wearing knee braces on unsteadiness on standing in a case with primary orthostatic tremor
Objective: To clarify the effect of wearing knee braces (KB) on unsteadiness on standing in a case with primary orthostatic tremor (OT) using stabilometry and…
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