Management of parkinsonian patients with long-term DBS and incomplete control of symptoms
Objective: We want to evaluate if apomorphine infusions can improve symptom control in PD patients with long standing DBS and functional decline. Background: Deep brain stimulation…Efficacy and Safety of High Doses of Safinamide in Advanced Parkinson’s Disease Patients in a Real-World Experience
Objective: To evaluate in a real-world experience high doses of safinamide in patients with fluctuating Parkinson's disease (PD). Background: Standard doses of safinamide (50-100 mg)…Dyskinesia and bradykinesia severity patterns in Parkinson’s disease using a wearable sensor
Objective: To determine if dyskinesia and bradykinesia severity has a diurnal pattern in Parkinson’s disease (PD) using wearable sensor data. Background: Diurnal fluctuations in PD…A pilot study on the shift from rasagiline to safinamide in fluctuating Parkinson’s disease patients
Objective: Here we investigated the consequences of the shift from rasagiline (RS) to SF in fluctuating PD patients. To this end, we selected patients from…Freezing of gait that persists from the OFF to the ON state is associated with memory impairments in Parkinson’s disease
Objective: To examine cognitive correlates associated with FOG that persists in both the ON and OFF medication states (ONOFF-FOG) vs. FOG that appears only in…Inhaled levodopa (LD) as a treatment for Parkinson’s disease (PD) patients in an emergency setting
Objective: To report on use of CVT-301 (inhaled LD) to treat PD patients with complicated OFF period symptoms who present to the emergency department (ED).…Intrinsic brain functional connectivity predicts treatment-related motor complications in drug-naive Parkinson’s disease patients
Objective: Using resting-state functional MRI, we investigated intrinsic brain networks connectivity at baseline in a cohort of drug-naïve Parkinson’s disease (PD) patients which successively developed treatment-related…Psychometric properties of clinical indicators of device-aided therapy eligibility among Parkinson’s disease patients: Real-world data from 6 countries
Objective: Evaluate the performance of clinical indicators for Device-aided Therapy (DAT) eligibility in real-world setting. Background: Timely initiation of appropriate DAT may improve quality of…Non-Motor Fluctuations in Parkinson’s Disease (PD): Development and Validation of the Non-Motor Fluctuation Assessment Instrument (NoMoFA)
Objective: Validate and demonstrate reliability of the NoMoFA. Background: In patients with PD, sleep, mood, cognitive, autonomic and other non-motor symptoms (NMS) may fluctuate (NMF)…Early detection of Parkinson’s disease motor fluctuations with a wearable inertial sensor
Objective: To assess the utility of a wearable inertial sensor for detecting motor complications in Parkinson’s disease (PD) and its usability. Background: Identifying motor complications…
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