MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Wearing-off fluctuations"

  • MDS Virtual Congress 2020

    Real-World Evidence for a Smartwatch-based Parkinson’s Motor Assessment App in Patients Undergoing Therapy Changes

    A. Hadley, D. Riley, D. Heldman (Cleveland, OH, USA)

    Objective: We sought to investigate patient and clinician usability of a smartwatch-based wearable motor assessment system for measuring Parkinson’s disease (PD) motor symptoms in patients undergoing…
  • MDS Virtual Congress 2020

    CVT-301 treatment provides consistent and clinically significant improvements in Unified Parkinson’s Disease Rating Scale Part III (UPDRS-III) over 12 weeks

    A. Ellenbogen, A. Corbin, P. Zhao, D. Kegler-Ebo, H. Roberts (Bingham Farms, MI, USA)

    Objective: A post hoc analysis of UPDRS-III sequential changes over the 12-week treatment period of a phase 3 study. Background: CVT-301 is an inhaled levodopa…
  • MDS Virtual Congress 2020

    Instrumented Detection of Fluctuations with Wearable Devices in Parkinson’s Disease

    G. Rigas, D. Kakalou, N. Tachos, K. Tsamis, N. Kostikis, A. Marcante, R. Di Mitri, M. Di Pumpo, S. Konitsiotis, D. Fotiadis (Ioannina, Greece)

    Objective: The objective of this study is to evaluate the efficacy in fluctuations detection of a system consisting of wearable devices embedding Inertial Measurement Units…
  • MDS Virtual Congress 2020

    Among Parkinson’s disease patients with both OFF and dyskinesia, ADS-5102 (amantadine) extended-release reduces disruptive motor episodes and improves function: Analysis of phase 3 trials

    R.A Hauser, D. Chernick, A. Formella (Tampa, FL, USA)

    Objective: Evaluate the effects of ADS-5102 (amantadine) extended release capsules on motor complications and functional outcomes among patients experiencing both troublesome dyskinesia and OFF (disruptive…
  • MDS Virtual Congress 2020

    Use in Clinical Practice of a Personalised and Long-term Monitoring Device for Parkinson´s Disease: STAT-ON

    D. Santos García, N. López Ariztegui, E. Cubo, A. Vinagre Aragón, R. García Ramos, C. Borrué, G. Fernández Pajarín, N. Caballol, I. Cabo, J. Barrios López, J. Hernández Vara, M.A Avila, C. Gasca Salas, S. Escalante, P. Manrique, R. Pérez Noguera, M. Álvarez Sauco, M. Sierra, M.G Monje, A. Sánchez Ferro, S. Novo, F. Alonso, D. Macías, I. Legarda, A. Rojo, I. Fernández, M.T Buongiorno, P. Pastor, P. García Ruíz (A Coruña, Spain)

    Objective: To analyze the opinion of different neurologists from Spain about the STAT-ON tool after using the device in a real clinical practice setting (RCPS).…
  • MDS Virtual Congress 2020

    Reduction of OFF time with apomorphine infusion during hours of pump use: Analysis from a Phase III, open-label study

    S. Isaacson, A. Espay, R. Pahwa, T. Clinch, P. LeWitt (Boca Raton, FL, USA)

    Objective: Evaluate the efficacy of apomorphine (APO) infusion in reducing OFF time during the hours of pump use in PD patients with motor fluctuations inadequately…
  • MDS Virtual Congress 2020

    Long-term effects of ADS-5102 (amantadine) extended release capsules on OFF symptoms in Parkinson’s disease patients with levodopa-induced dyskinesia: Analysis of EASE LID 2 trial

    C. Tanner, D. Chernick, A. Formella (San Francisco, CA, USA)

    Objective: Evaluate the long-term effect of ADS-5102 on OFF time among Parkinson’s disease (PD) patients with levodopa-induced dyskinesia (LID). Background: ADS-5102, the only drug FDA-approved…
  • MDS Virtual Congress 2020

    Levodopa and dopamine agonists dosage changes after Opicapone introduction

    N. Caballol, A. Planas-Ballvé, A. Ávila (Sant Joan Despí, Spain)

    Objective: We aim to analyze changes in levodopa and dopamine agonists (DA) dosage after introduction of opicapone (OPC) in a daily clinical practice setting. Background:…
  • MDS Virtual Congress 2020

    Motor subtype change between OFF and ON periods in patients with Parkinson’s disease

    O. Esquivel-Zapata, A. Abundes-Corona, F. Herrera-Rodriguez, O. Cardenas-Saenz, E. Escobar-Valdivia, Y. Ríos-Solís, H. Tellez-Lucero, A. Cervantes-Arriaga, M. Rodriguez-Violante (Mexico, Mexico)

    Objective: To identify if there is any difference in the motor subtype of PwPD between "off" stage and "on" stage. Background: Patients with Parkinson’s disease…
  • MDS Virtual Congress 2020

    Efficacy and tolerability of opicapone in Parkinson´s disease in usual clinical practice

    V. Gomez-Mayordomo, F. Alonso-Frech, E. Lopez-Valdes, R. Garcia-Ramos, M. Catalan-Alonso (Madrid, Spain)

    Objective: To evaluate the efficacy and tolerability of opicapone in usual clinical practice in patients with Parkinson's disease (PD). Background: Opicapone is a recently approved…
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